Copper homeostasis and cuproptosis in health and disease

L Chen, J Min, F Wang - Signal transduction and targeted therapy, 2022 - nature.com
As an essential micronutrient, copper is required for a wide range of physiological processes
in virtually all cell types. Because the accumulation of intracellular copper can induce …

Copper dyshomeostasis in neurodegenerative diseases—therapeutic implications

G Gromadzka, B Tarnacka, A Flaga… - International journal of …, 2020 - mdpi.com
Copper is one of the most abundant basic transition metals in the human body. It takes part
in oxygen metabolism, collagen synthesis, and skin pigmentation, maintaining the integrity …

[图书][B] Developmental neuropsychology: A clinical approach

V Anderson, E Northam, J Wrennall - 2018 - taylorfrancis.com
This fully updated edition of Developmental Neuropsychology: A Clinical Approach
addresses key issues in child neuropsychology with a unique emphasis on evidence …

Wilson's disease

A Ala, AP Walker, K Ashkan, JS Dooley, ML Schilsky - The Lancet, 2007 - thelancet.com
Progressive hepatolenticular degeneration, or Wilson's disease, is a genetic disorder of
copper metabolism. Knowledge of the clinical presentations and treatment of the disease …

The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases

P Dusek, PM Roos, T Litwin, SA Schneider… - Journal of trace …, 2015 - Elsevier
Impaired cellular homeostasis of metals, particularly of Cu, Fe and Mn may trigger
neurodegeneration through various mechanisms, notably induction of oxidative stress …

Wilson's disease: A 2017 update

A Poujois, F Woimant - Clinics and research in hepatology and …, 2018 - Elsevier
Wilson's disease (WD) is characterised by a deleterious accumulation of copper in the liver
and brain. It is one of those rare genetic disorders that benefits from effective and lifelong …

Investigation and management of Wilson's disease: a practical guide from the British Association for the Study of the Liver

S Shribman, T Marjot, A Sharif… - The Lancet …, 2022 - thelancet.com
Wilson's disease is an autosomal-recessive disorder of copper metabolism with hepatic,
neurological, psychiatric, ophthalmological, haematological, renal, and rheumatological …

Wilson's disease: clinical practice guidelines of the Indian national association for study of the liver, the Indian society of pediatric gastroenterology, hepatology and …

A Nagral, MS Sarma, J Matthai, PL Kukkle… - Journal of clinical and …, 2019 - Elsevier
Clinical practice guidelines for Wilson's disease (WD) have been published by the American
Association for the Study of Liver Diseases and European Association for the Study of the …

Wilson disease: description of 282 patients evaluated over 3 decades

AB Taly, S Meenakshi-Sundaram, S Sinha, HS Swamy… - Medicine, 2007 - journals.lww.com
The clinical manifestations of Wilson disease (WD) are varied and challenging. We
conducted the current study to present the phenotypic characteristics and follow-up for a …

Copper handling machinery of the brain

S Lutsenko, A Bhattacharjee, AL Hubbard - Metallomics, 2010 - academic.oup.com
Copper plays an indispensable role in the physiology of the human central nervous system
(CNS). As a cofactor of dopamine-β-hydroxylase, peptidyl-α-monooxygenase, superoxide …