Allergic rhinitis is clinically defined as a symptomatic disorder of the nose induced by an IgE-
mediated inflammation after allergen exposure of the membranes lining the nose. Symptoms …

Asthma is the leading chronic disease among children in most industrialized countries.
However, the evidence base on specific aspects of pediatric asthma, including therapeutic …

Background It is unknown whether inhaled corticosteroids can modify the subsequent
development of asthma in preschool children at high risk for asthma. Methods We randomly …

Objective To appraise the data on systemic adverse effects of inhaled corticosteroids.
Methods A computerized database search from January 1, 1966, through July 31, 1998 …

Background Antiinflammatory therapies, such as inhaled corticosteroids or nedocromil, are
recommended for children with asthma, although there is limited information on their long …

Background Daily inhaled corticosteroids are an effective treatment for mild persistent
asthma, but some children have exacerbations even with good day-to-day control, and many …

Background: Long-acting β-agonists may increase the risk for fatal and nonfatal asthma
exacerbations. Purpose: To assess the risk for severe, life-threatening, or fatal asthma …

Background Patients with mild asthma frequently have only exercise-induced
bronchoconstriction, a symptom of inadequate control of asthma. We evaluated the ability of …

Background Short-term studies have shown that inhaled corticosteroids may reduce the
growth of children with asthma. However, the effect of long-term treatment on adult height is …

Background. The greatest prevalence of asthma is in preschool children; however, the
clinical utility of asthma therapy for this age group is limited by a narrow therapeutic index …