An updated advance of autoantibodies in autoimmune diseases
Autoantibodies are abnormal antibodies which are generated by pathogenic B cells when
targeting an individual's own tissue. Autoantibodies have been identified as a symbol of …
targeting an individual's own tissue. Autoantibodies have been identified as a symbol of …
B cell activating factor (BAFF): structure, functions, autoimmunity and clinical implications in systemic lupus erythematosus (SLE)
T Möckel, F Basta, J Weinmann-Menke… - Autoimmunity reviews, 2021 - Elsevier
The B cell activating factor (BAFF), or B lymphocyte stimulator (BLyS), is a B cell survival
factor which supports autoreactive B cells and prevents their deletion. BAFF expression is …
factor which supports autoreactive B cells and prevents their deletion. BAFF expression is …
The pathogenesis of rheumatoid arthritis
IB McInnes, G Schett - New England Journal of Medicine, 2011 - Mass Medical Soc
The Pathogenesis of Rheumatoid Arthritis | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …
content The New England Journal of Medicine homepage Advanced Search SEARCH …
Rheumatoid arthritis: recent advances on its etiology, role of cytokines and pharmacotherapy
J Alam, I Jantan, SNA Bukhari - Biomedicine & pharmacotherapy, 2017 - Elsevier
An autoimmune disease is defined as a clinical syndrome resulted from an instigation of
both T cell and B cell or individually, in the absence of any present infection or any sort of …
both T cell and B cell or individually, in the absence of any present infection or any sort of …
Cytokines in the pathogenesis of rheumatoid arthritis
IB McInnes, G Schett - Nature Reviews Immunology, 2007 - nature.com
Cytokines regulate a broad range of inflammatory processes that are implicated in the
pathogenesis of rheumatoid arthritis. In rheumatoid joints, it is well known that an imbalance …
pathogenesis of rheumatoid arthritis. In rheumatoid joints, it is well known that an imbalance …
Emerging cell and cytokine targets in rheumatoid arthritis
Despite major progress in the treatment of rheumatoid arthritis (RA), strong unmet medical
need remains, as only a minor proportion of patients reach sustained clinical remission. New …
need remains, as only a minor proportion of patients reach sustained clinical remission. New …
Lymphoid neogenesis in chronic inflammatory diseases
F Aloisi, R Pujol-Borrell - Nature Reviews Immunology, 2006 - nature.com
The frequent observation of organized lymphoid structures that resemble secondary
lymphoid organs in tissues that are targeted by chronic inflammatory processes, such as …
lymphoid organs in tissues that are targeted by chronic inflammatory processes, such as …
The role and therapeutic implications of fibroblast‐like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis
EH Noss, MB Brenner - Immunological reviews, 2008 - Wiley Online Library
Fibroblast‐like synoviocytes (FLS) are resident mesenchymal cells of synovial joints that
have been recognized to play an increasingly important role in the pathogenesis of …
have been recognized to play an increasingly important role in the pathogenesis of …
Mechanisms of disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis
U Müller-Ladner, T Pap, RE Gay, M Neidhart… - Nature clinical practice …, 2005 - nature.com
Rheumatoid arthritis is a complex systemic disease that ultimately leads to the progressive
destruction of articular and periarticular structures. Novel data indicate that the innate …
destruction of articular and periarticular structures. Novel data indicate that the innate …
Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1α
M Nishio, T Endo, N Tsukada, J Ohata, S Kitada… - Blood, 2005 - ashpublications.org
We examined expression of B cell–a ctivating f actor of the tumor necrosis factor (TNF) f
amily (BAFF) and a pr oliferation-i nducing l igand (APRIL) on chronic lymphocytic leukemia …
amily (BAFF) and a pr oliferation-i nducing l igand (APRIL) on chronic lymphocytic leukemia …