Aminoglycoside uptake, stress, and potentiation in Gram-negative bacteria: new therapies with old molecules

M Lang, A Carvalho, Z Baharoglu… - … and Molecular Biology …, 2023 - Am Soc Microbiol
Aminoglycosides (AGs) are long-known molecules successfully used against Gram-negative
pathogens. While their use declined with the discovery of new antibiotics, they are now …

Regulation of bacterial metabolism by small RNAs using diverse mechanisms

M Bobrovskyy, CK Vanderpool - Annual review of genetics, 2013 - annualreviews.org
Bacteria live in many dynamic environments with alternating cycles of feast or famine that
have resulted in the evolution of mechanisms to quickly alter their metabolic capabilities …

Regulation of Hfq by the RNA CrcZ in Pseudomonas aeruginosa Carbon Catabolite Repression

E Sonnleitner, U Bläsi - PLoS Genetics, 2014 - journals.plos.org
Carbon Catabolite repression (CCR) allows a fast adaptation of Bacteria to changing
nutrient supplies. The Pseudomonas aeruginosa (PAO1) catabolite repression control …

The Crc and Hfq proteins of Pseudomonas putida cooperate in catabolite repression and formation of ribonucleic acid complexes with specific target motifs

R Moreno, S Hernández‐Arranz… - Environmental …, 2015 - Wiley Online Library
The Crc protein is a global regulator that has a key role in catabolite repression and
optimization of metabolism in Pseudomonads. Crc inhibits gene expression post …

Specific and Global RNA Regulators in Pseudomonas aeruginosa

P Pusic, E Sonnleitner, U Bläsi - International Journal of Molecular …, 2021 - mdpi.com
Pseudomonas aeruginosa (Pae) is an opportunistic pathogen showing a high intrinsic
resistance to a wide variety of antibiotics. It causes nosocomial infections that are particularly …

Identification of Indole-3-Acetic Acid-Regulated Genes in Pseudomonas syringae pv. tomato Strain DC3000

AT Djami-Tchatchou, ZA Li, P Stodghill… - Journal of …, 2022 - Am Soc Microbiol
The auxin indole-3-acetic acid (IAA) is a plant hormone that not only regulates plant growth
and development but also plays important roles in plant-microbe interactions. We previously …

Carbohydrate utilization in bacteria: making the most out of sugars with the help of small regulatory RNAs

S Durica-Mitic, Y Göpel, B Görke - Regulating with RNA in …, 2018 - Wiley Online Library
Carbohydrates are degraded in central metabolic pathways, namely, glycolysis, the pentose
phosphate pathway, and the tricarboxylic acid (TCA) cycle, to fuel cells with energy and …

Pseudomonad reverse carbon catabolite repression, interspecies metabolite exchange, and consortial division of labor

H Park, SL McGill, AD Arnold, RP Carlson - Cellular and Molecular Life …, 2020 - Springer
Microorganisms acquire energy and nutrients from dynamic environments, where substrates
vary in both type and abundance. The regulatory system responsible for prioritizing …

Implications of carbon catabolite repression for plant–microbe interactions

T Franzino, H Boubakri, T Cernava, D Abrouk… - Plant …, 2022 - cell.com
Carbon catabolite repression (CCR) plays a key role in many physiological and adaptive
responses in a broad range of microorganisms that are commonly associated with …

Integrated regulatory network in Pseudomonas syringae reveals dynamics of virulence

X Shao, M Tan, Y Xie, C Yao, T Wang, H Huang… - Cell Reports, 2021 - cell.com
Pseudomonas syringae, a Gram-negative plant pathogen, expresses multitudinous
transcriptional regulators to control the type III secretion system (T3SS) and response to …