Significance: Under homeostatic conditions, the endothelium dynamically regulates vascular
barrier function, coagulation pathways, leukocyte adhesion, and vasomotor tone. During …

Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-
domain macromolecule, representing the main determinant of plasma oncotic pressure and …

Background Although previous studies have suggested the potential advantages of albumin
administration in patients with severe sepsis, its efficacy has not been fully established …

Human serum albumin (HSA) is an abundant mul-tifunctional non-glycosylated, negatively
charged plasma protein, with ascribed ligand-binding and transport properties, antioxidant …

Human serum albumin (HSA) has been used for a long time as a resuscitation fluid in
critically ill patients. It is known to exert several important physiological and pharmacological …

Objective To determine whether hypoalbuminemia is an independent risk factor for poor
outcome in the acutely ill, and to assess the potential of exogenous albumin administration …

Objective To assess the efficacy and safety of pooled human albumin solutions as part of
fluid volume expansion and resuscitation (with or without improvement of baseline …

Albumin is the main determinant of plasma oncotic pressure and it plays a pivotal role in
modulating the distribution of fluids between compartments. Moreover, it has many other …

Objective: To assess whether resuscitation with albumin-containing solutions, compared
with other fluids, is associated with lower mortality in patients with sepsis. Data Sources …

Human serum albumin is a critical plasma protein produced by the liver with a number of
accepted clinical indications in chronic liver disease including management of circulatory …