During the process of implantation, the embryo first attaches to the uterine epithelium and
then invades the underlying stroma, resulting in the transformation of the stroma into a …

Implantation of the embryo into the uterine endometrium is one of the most finely-regulated
processes that leads to the establishment of a successful pregnancy. A plethora of factors …

Spatially ordered embryo-like structures self-assembled from blastocyst-derived stem cells
can be generated to mimic embryogenesis in vitro. However, the assembly system and …

The uterine luminal epithelium (LE) is the first maternal contact for an implanting embryo.
Intrauterine fluid resorption, cessation of LE proliferation and apoptosis, and LE structural …

Research in developmental biology has been recently enriched by a multitude of in vitro
models recapitulating key milestones of mammalian embryogenesis. These models obviate …

The Notch signaling pathway is conserved among mammalian species and controls
proliferation, differentiation, and cell death in many organs throughout the body including the …

During decidualization in rodents, uterine stroma undergoes extensive reprograming into
distinct cells, forming the discrete regions defined as the primary decidual zone (PDZ), the …

During early pregnancy in the mouse, nidatory estrogen (E2) stimulates endometrial
receptivity by activating a network of signaling pathways that is not yet fully characterized …

Infertility and subfertility negatively impact the economics and reproductive performance of
cattle. Of note, significant pregnancy loss occurs in cattle during the first month of pregnancy …

Members of the transforming growth factor β (TGF-β) superfamily are key regulators in most
developmental and physiological processes. However, the in vivo roles of TGF-β signaling …