Effectiveness and safety of sofosbuvir/velpatasvir/voxilaprevir as a hepatitis C virus infection salvage therapy in the real world: a systematic review and meta-analysis

J Xie, B Xu, L Wei, C Huang, W Liu - Infectious diseases and therapy, 2022 - Springer
Abstract Introduction Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX) is the first direct-
acting antiviral (DAA) therapy approved for patients who have previously failed a DAA …

New direct-acting antivirals for the treatment of patients with hepatitis C virus infection: a systematic review of randomized controlled trials

V Pecoraro, R Banzi, E Cariani, J Chester… - Journal of clinical and …, 2019 - Elsevier
Background New direct-acting antiviral agents (DAAs) approved for the treatment of patients
infected by Hepatitis C virus (HCV) are well tolerated and increase sustained virological …

Machine learning algorithms for predicting direct‐acting antiviral treatment failure in chronic hepatitis C: An HCV‐TARGET analysis

H Park, WH Lo‐Ciganic, J Huang, Y Wu, L Henry… - …, 2022 - Wiley Online Library
Abstract Background and Aims We aimed to develop and validate machine learning
algorithms to predict direct‐acting antiviral (DAA) treatment failure among patients with HCV …

Self-reported and measured adherence to hepatitis C direct-acting antiviral therapy and sustained virologic response among people who inject drugs: The HERO …

SS Lopes, I Pericot-Valverde, J Arnsten, PJ Lum… - International Journal of …, 2024 - Elsevier
Background Objective adherence measures, such as electronic blister pack (BP), for direct-
acting antivirals (DAAs) for hepatitis C virus (HCV) treatment have high accuracy, but their …

Rate and predictors of treatment failure to all-oral HCV regimens outside clinical trials

A Arias, A Aguilera, V Soriano… - Antiviral …, 2017 - journals.sagepub.com
Background Cure rates above 90% have been reported in most Phase III clinical trials using
distinct all-oral direct-acting antivirals (DAAs) in chronic hepatitis C patients. Preliminary …

Efficacy and safety of generic sofosbuvir plus daclatasvir and sofosbuvir/velpatasvir in HCV genotype 3-infected patients: real-world outcomes from Pakistan

S Mushtaq, TS Akhter, A Khan, A Sohail… - Frontiers in …, 2020 - frontiersin.org
Background Direct-acting antivirals (DAAs) therapeutic regimens are highly effective against
chronic hepatitis C virus (HCV) infection. However, HCV patients with genotype 3 (GT3) …

Sofosbuvir/velpatasvir/voxilaprevir for patients with chronic hepatitis C virus infection previously treated with NS5A direct-acting antivirals: a real-world multicenter …

CH Liu, CY Peng, CJ Liu, CY Chen, CC Lo… - Hepatology …, 2023 - Springer
Background Real-world data are scarce about the effectiveness and safety of
sofosbuvir/velpatasvir/voxilaprevir (SOF/VEL/VOX) for retreating East Asian patients with …

Hepatitis C virus resistance to the new direct-acting antivirals

I Esposito, J Trinks, V Soriano - Expert opinion on drug metabolism …, 2016 - Taylor & Francis
Introduction: The treatment of hepatitis C virus (HCV) infection has dramatically improved in
recent years with the widespread use of interferon-free combination regimens. Despite the …

Host-targeting therapies for hepatitis C virus infection: current developments and future applications

E Crouchet, F Wrensch, C Schuster… - Therapeutic …, 2018 - journals.sagepub.com
Chronic hepatitis C virus (HCV) infection is a leading cause of chronic liver diseases and
hepatocellular carcinoma (HCC) worldwide. In the past few years, anti-HCV therapies have …

Efficacy and safety of alisporivir for the treatment of hepatitis C infection

C Stanciu, A Trifan, C Muzica… - Expert Opinion on …, 2019 - Taylor & Francis
ABSTRACT Introduction: Alisporivir (ALV)(previously known as Debio 025) is a potent,
pangenotypic host-targeting antiviral oral agent acting on cyclophilin A, which is necessary …