The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …

Anoikis is a programmed cell death induced upon cell detachment from extracellular matrix,
behaving as a critical mechanism in preventing adherent-independent cell growth and …

Paracrine is an important mechanism in mesenchymal stem cells (MSCs) that promotes
tissue regeneration. However, anoikis is attributed to unsuitable adhesion microenvironment …

Silk fibroin (SF) was enzymatically crosslinked with tyramine-substituted silk fibroin (SF-TA)
or gelatin (G-TA) to fabricate hybrid hydrogels with tunable gelation kinetics, mechanical …

Endothelial progenitor cells (EPCs) are a promising cell source for the treatment of several
ischemic diseases for their potentials in neovascularization. However, the application of …

The extracellular matrix (ECM) is an important component of the tumor microenvironment
(TME), having several important roles related to the hallmarks of cancer. In cancer, multiple …

An association between human papillomavirus (HPV) infection and the development of
cervical cancer was initially reported over 30 years ago, and today there is overwhelming …

Cell attachment to the extracellular matrix (ECM) is crucial to cell physiology such as
polarity, motility, and proliferation. In normal cells, loss of attachment to the ECM induces a …

RAS proteins are small GTPases known for their involvement in oncogenesis: around 25%
of human tumors present mutations in a member of this family. RAS operates in a complex …

Cancer metastasis is the dissemination of tumor cells to new sites, resulting in the formation
of secondary tumors. This process is complex and is spatially and temporally regulated by …