Mechanism of action and biology of flow diverters in the treatment of intracranial aneurysms

K Ravindran, AM Casabella, J Cebral, W Brinjikji… - …, 2020 - journals.lww.com
Flow diverters have drastically changed the landscape of intracranial aneurysm treatment
and are now considered first-line therapy for select lesions. Their mechanism of action relies …

Intravascular optical coherence tomography for neurointerventional surgery

MJ Gounis, GJ Ughi, M Marosfoi, DK Lopes, D Fiorella… - Stroke, 2019 - Am Heart Assoc
Gounis et al Intravascular OCT for Neurointervention 219 underexpansion and other
predictors of cardiovascular events, including edge dissections, intraluminal thrombus, thin …

[HTML][HTML] A neurovascular high-frequency optical coherence tomography system enables in situ cerebrovascular volumetric microscopy

GJ Ughi, MG Marosfoi, RM King, J Caroff… - Nature …, 2020 - nature.com
Intravascular imaging has emerged as a valuable tool for the treatment of coronary and
peripheral artery disease; however, no solution is available for safe and reliable use in the …

Acute thrombus formation on phosphorilcholine surface modified flow diverters

M Marosfoi, F Clarencon, ET Langan… - Journal of …, 2018 - jnis.bmj.com
Purpose Thromboembolic complications remain a limitation of flow diverting stents. We
hypothesize that phosphorilcholine surface modified flow diverters (Pipeline Flex with Shield …

Endovascular treatment of very large and giant intracranial aneurysms: comparison between reconstructive and deconstructive techniques—a meta-analysis

F Cagnazzo, D Mantilla, A Rouchaud… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND: The safety and efficacy of reconstructive and deconstructive endovascular
treatments of very large/giant intracranial aneurysms are not completely clear. PURPOSE …

Endothelialization following flow diversion for intracranial aneurysms: a systematic review

K Ravindran, MM Salem, AY Alturki… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND: The underlying mechanism of action of flow diverters is believed to be the
induction of aneurysm thrombosis and simultaneous endothelial cell growth along the …

Determinants of cerebral aneurysm occlusion after embolization with the WEB device: a single-institution series of 215 cases with angiographic follow-up

J Cortese, J Caroff, V Chalumeau, S Gallas… - Journal of …, 2023 - jnis.bmj.com
Background Woven EndoBridge (WEB) devices are becoming a reliable option for the
treatment of wide-neck bifurcation aneurysms, but clear predictive factors are still missing to …

Patterns of neointima formation after coil or stent treatment in a rat saccular sidewall aneurysm model

BE Grüter, S Wanderer, F Strange, G Boillat, D Täschler… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Endovascular aneurysm treatment relies on a biological process,
including cell migration for thrombus organization and growth of a neointima. To better …

Overview of different flow diverters and flow dynamics

GA Maragkos, AA Dmytriw, MM Salem, VM Tutino… - …, 2020 - journals.lww.com
Over the past decade, flow diverter technology for endocranial aneurysms has seen rapid
evolution, with the development of new devices quickly outpacing the clinical evidence …

Bioresorbable poly (L-lactic acid) flow diverter versus cobalt-chromium flow diverter: in vitro and in vivo analysis

N Sasaki, A Ishii, S Yagi, H Nishi, R Akiyama, M Okawa… - Stroke, 2023 - Am Heart Assoc
Background: Permanent metallic flow diverter (FD) implantation for treatment of intracranial
aneurysms requires antiplatelet therapy for an unclear duration and restricts postprocedural …