[Retracted] Targeting AraC‐Resistant Acute Myeloid Leukemia by Dual Inhibition of CDK9 and Bcl‐2: A Systematic Review and Meta‐Analysis

L Li, C Han, X Yu, J Shen, Y Cao - Journal of Healthcare …, 2022 - Wiley Online Library
Purpose. This study aims to determine the influence of targeting araC‐resistant acute
myeloid leukemia by dual inhibition cyclin‐dependent protein kinase (CDK9) and B‐cell …

Cytarabine-induced differentiation of AML cells depends on Chk1 activation and shares the mechanism with inhibitors of DHODH and pyrimidine synthesis

B Tomic, T Smoljo, H Lalic, V Dembitz, J Batinic… - Scientific reports, 2022 - nature.com
Acute myeloid leukemia (AML) is characterized by arrested differentiation making
differentiation therapy a promising treatment strategy. Recent success of inhibitors of …

Bone marrow stromal cells reduce low-dose cytarabine-induced differentiation of acute myeloid leukemia

T Smoljo, B Tomic, H Lalic, V Dembitz… - Frontiers in …, 2023 - frontiersin.org
Low-dose cytarabine (LDAC) is a standard therapy for elderly acute myeloid leukemia (AML)
patients unfit for intensive chemotherapy. While high doses of cytarabine induce cytotoxicity …

Decoding the mechanism of Shen Qi Sha Bai decoction in treating acute myeloid leukemia based on network pharmacology and molecular docking

G Jia, X Jiang, Z Li, X Ding, L Lei, S Xu… - Frontiers in Cell and …, 2021 - frontiersin.org
Traditional Chinese Medicine (TCM) has been shown to be efficacious in treating leukemia
for thousands of years. It has been shown that Shen Qi Sha Bai Decoction (SQSBD) has …

Bone Marrow Stromal Cells Enhance Differentiation of Acute Myeloid Leukemia Induced by Pyrimidine Synthesis Inhibitors

T Smoljo, H Lalic, V Dembitz, B Tomic… - … of Physiology-Cell …, 2024 - journals.physiology.org
Acute myeloid leukemia (AML) is a heterogeneous group of hematologic malignancies
characterized by differentiation arrest, high relapse rates, and poor survival. The bone …

miR‑let‑7c‑3p targeting on Egr‑1 contributes to the committed differentiation of leukemia cells into monocyte/macrophages

F Qi, X Wang, S Zhao, C Wang, R Sun… - Oncology …, 2022 - spandidos-publications.com
In preliminary experiments, it was found that the expression of early growth response‑1 (Egr‑
1) was upregulated during the committed differentiation of leukemia cells into monocytes …

[PDF][PDF] Barbara Tomic1, 2, Tomislav Smoljo1, 2, Hrvoje Lalic1, 2, Vilma Dembitz1, 2, Josip Batinic3

D Batinic, A Bedalov, D Visnjic - Scientific Reports, 2022 - bib.irb.hr
Acute myeloid leukemia (AML) is characterized by arrested differentiation making
differentiation therapy a promising treatment strategy. Recent success of inhibitors of …

Mehanizam diferencijacije stanica akutne mijeloične leukemije potaknute citarabinom

T Smoljo - 2024 - repozitorij.unizg.hr
Sažetak Citarabin u malim koncentracijama potiče diferencijaciju stanica akutne mijeloične
leukemije (AML), ali mehanizam nije u potpunosti objašnjen. Naša prethodna istraživanja …