Dopamine and addiction

RA Wise, MA Robble - Annual review of psychology, 2020 - annualreviews.org
Addiction is commonly identified with habitual nonmedical self-administration of drugs. It is
usually defined by characteristics of intoxication or by characteristics of withdrawal …

Understanding opioid reward

HL Fields, EB Margolis - Trends in neurosciences, 2015 - cell.com
Opioids are the most potent analgesics in clinical use; however, their powerful rewarding
properties can lead to addiction. The scientific challenge is to retain analgesic potency while …

[图书][B] Affect regulation and the origin of the self: The neurobiology of emotional development

AN Schore - 2015 - taylorfrancis.com
For over three decades, Allan N. Schore has authored numerous volumes, chapters, and
articles on regulation theory, a biopsychosocial model of the development …

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

G Di Chiara, A Imperato - Proceedings of the National …, 1988 - National Acad Sciences
The effect of various drugs on the extracellular concentration of dopamine in two terminal
dopaminergic areas, the nucleus accumbens septi (a limbic area) and the dorsal caudate …

Dopamine, learning and motivation

RA Wise - Nature reviews neuroscience, 2004 - nature.com
The hypothesis that dopamine is important for reward has been proposed in a number of
forms, each of which has been challenged. Normally, rewarding stimuli such as food, water …

A psychomotor stimulant theory of addiction.

RA Wise, MA Bozarth - Psychological review, 1987 - psycnet.apa.org
The theory is advanced that the common denominator of a wide range of addictive
substances is their ability to cause psychomotor activation. This view is related to the theory …

Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake

NM Avena, P Rada, BG Hoebel - Neuroscience & Biobehavioral Reviews, 2008 - Elsevier
[Avena, NM, Rada, P., Hoebel BG, 2007. Evidence for sugar addiction: Behavioral and
neurochemical effects of intermittent, excessive sugar intake. Neuroscience and …

Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens–olfactory tubercle complex

S Ikemoto - Brain research reviews, 2007 - Elsevier
Anatomical and functional refinements of the meso-limbic dopamine system of the rat are
discussed. Present experiments suggest that dopaminergic neurons localized in the …

Opiate versus psychostimulant addiction: the differences do matter

A Badiani, D Belin, D Epstein, D Calu… - Nature reviews …, 2011 - nature.com
The publication of the psychomotor stimulant theory of addiction in 1987 and the finding that
addictive drugs increase dopamine concentrations in the rat mesolimbic system in 1988 …

The many faces of CREB

WA Carlezon, RS Duman, EJ Nestler - Trends in neurosciences, 2005 - cell.com
The transcription factor CREB is best known for its involvement in learning and memory.
However, emerging evidence suggests that CREB activity has very different roles …