C–C bond cleavages of cyclopropenes: operating for selective ring-opening reactions

R Vicente - Chemical Reviews, 2020 - ACS Publications
This review highlights key reactivities relying on C–C bond cleavages of cyclopropenes.
Metal-catalyzed and metal-free transformations are covered in reactions involving direct ring …

Creating stereocenters within acyclic systems by C–C bond cleavage of cyclopropanes

Y Cohen, A Cohen, I Marek - Chemical Reviews, 2020 - ACS Publications
Recent developments in the stereoselective synthesis of polysubstituted cyclopropanes
nowadays allow chemists to easily access these strained rings with high diastereo-and …

Asymmetric Preparation of Polysubstituted Cyclopropanes Based on Direct Functionalization of Achiral Three-Membered Carbocycles: Focus Review

L Dian, I Marek - Chemical reviews, 2018 - ACS Publications
In addition to the appealing synthetic transformations that cyclopropanes present, they are
also part of larger molecular structures that possess a wide range of biological properties …

Regio-and diastereoselective carbometalation reaction of cyclopropenes

Y Cohen, I Marek - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus The various facets of the chemistry of cyclopropane derivatives, the smallest
carbocycle, are amazingly diverse and continue to fascinate theoreticians, synthetic or …

Recent developments in cyclopropene chemistry

P Li, X Zhang, M Shi - Chemical Communications, 2020 - pubs.rsc.org
The transformations of cyclopropenes have attracted the attention of organic chemists for
decades. As readily accessible strained carbocycles, cyclopropenes show a diverse range …

The Indenyl Effect: Accelerated C−H Amidation of Arenes via Ind*RhIII Nitrene Transfer Catalysis**

L Atkin, DL Priebbenow - Angewandte Chemie, 2023 - Wiley Online Library
Investigations into C− H amidation reactions catalysed by cationic half‐sandwich d6 metal
complexes revealed that the indenyl‐derived catalyst [Ind* RhCl2] 2 significantly accelerated …

Enantioselective construction of acyclic quaternary carbon stereocenters: palladium-catalyzed decarboxylative allylic alkylation of fully substituted amide enolates

P Starkov, JT Moore, DC Duquette… - Journal of the …, 2017 - ACS Publications
We report a divergent and modular protocol for the preparation of acyclic molecular
frameworks containing newly created quaternary carbon stereocenters. Central to this …

Asymmetric copper‐catalyzed carbomagnesiation of cyclopropenes

L Dian, DS Müller, I Marek - Angewandte Chemie International …, 2017 - Wiley Online Library
The highly diastereo‐and enantioselective formation of polysubstituted cyclopropanes was
easily achieved through the asymmetric copper‐catalyzed carbomagnesiation reaction of …

Efficient and stereodivergent synthesis of unsaturated acyclic fragments bearing contiguous stereogenic elements

J Bruffaerts, D Pierrot, I Marek - Nature chemistry, 2018 - nature.com
Synthetic organic strategies that enable the catalytic and rapid assembly of a large array of
organic compounds that possess multiple stereocentres in acyclic systems are somewhat …

Nucleophilic substitution at quaternary carbon stereocenters

V Lanke, I Marek - Journal of the American Chemical Society, 2020 - ACS Publications
Cyclopropyl carbinol derivatives undergo a regio-and stereoselective nucleophilic
substitution at the quaternary carbon center, with pure inversion of configuration, to provide …