Diabetic nephropathy is the leading cause of end‐stage kidney disease worldwide but
current treatments remain suboptimal. This review examines the evidence for inflammation …

Increasing incidences of obesity and diabetes have made diabetic kidney disease (DKD) the
leading cause of chronic kidney disease and end-stage renal disease worldwide. Despite …

Alzheimer's disease remains incurable, and the failures of current disease-modifying
strategies for Alzheimer's disease could be attributed to a lack of in vivo models that …

Different types of activated leukocytes play a crucial role in the pathogenesis of most kidney
diseases from acute to chronic stages; however, diabetic nephropathy was not considered …

Inflammation and its consequent fibrosis are two main features of diabetic nephropathy
(DN), but target therapy on these processes for DN remains yet ineffective. We report here …

Diabetes mellitus is a metabolic disorder that leads to the development of a number of
complications. The etiology of each diabetic complication is undoubtedly multifactorial. We …

Nitric oxide (NO) is a short-life molecule produced by the enzyme known as the nitric oxide
synthase (NOS), in a reaction that converts arginine and oxygen into citrulline and NO …

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting
from defects in insulin secretion and/or action. One of the most important complications of …

Diabetic nephropathy (DN) is the leading cause of end stage renal disease (ESRD).
Although the pathogenesis of DN is multifactorial, local inflammatory stress may result from …

Renal microvascular disease associated with diabetes [Diabetic kidney disease-DKD] is the
leading cause of chronic kidney disease. In DKD, glomerular basement membrane …