Advances in nanomaterial-based targeted drug delivery systems
X Cheng, Q Xie, Y Sun - Frontiers in bioengineering and …, 2023 - frontiersin.org
Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …
Tumor-associated macrophages and ovarian cancer: implications for therapy
Simple Summary Ovarian cancer is a highly lethal female malignancy with high rates of
advanced stage and recurrent disease. Ovarian cancer is characterized as poorly …
advanced stage and recurrent disease. Ovarian cancer is characterized as poorly …
The mechanisms of nanoparticle delivery to solid tumours
Nanoparticles for the detection and treatment of cancer have suffered from limited clinical
translation. A key problem has been the lack of understanding of the mechanisms of …
translation. A key problem has been the lack of understanding of the mechanisms of …
Engineering nanomaterial physical characteristics for cancer immunotherapy
The physical properties of nanomaterials—such as size, structure, shape, charge,
mechanical strength and hydrophobicity—can directly or indirectly influence immune cell …
mechanical strength and hydrophobicity—can directly or indirectly influence immune cell …
Nanomedicine strategies for heating “cold” ovarian cancer (OC): next evolution in immunotherapy of OC
Y Yang, T Zhao, Q Chen, Y Li, Z Xiao… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has revolutionized cancer treatment, dramatically improving survival rates of
melanoma and lung cancer patients. Nevertheless, immunotherapy is almost ineffective …
melanoma and lung cancer patients. Nevertheless, immunotherapy is almost ineffective …
Epigenetic crosstalk between hypoxia and tumor driven by HIF regulation
T Li, C Mao, X Wang, Y Shi, Y Tao - Journal of Experimental & Clinical …, 2020 - Springer
Hypoxia is the major influence factor in physiological and pathological courses which are
mainly mediated by hypoxia-inducible factors (HIFs) in response to low oxygen tensions …
mainly mediated by hypoxia-inducible factors (HIFs) in response to low oxygen tensions …
Strategies targeting tumor immune and stromal microenvironment and their clinical relevance
The critical role of tumor microenvironment (TME) in tumor initiation and development has
been well-recognized after more than a century of studies. Numerous therapeutic …
been well-recognized after more than a century of studies. Numerous therapeutic …
[HTML][HTML] Multifunctional nanoprobes for macrophage imaging
Imaging and tracking macrophage behaviors in vivo are essential to reveal its biological
function and fate in various diseases. Small molecular probes suffer from poor macrophage …
function and fate in various diseases. Small molecular probes suffer from poor macrophage …
A focus on “bio” in bio–nanoscience: the impact of biological factors on nanomaterial interactions
C Cortez‐Jugo, E Czuba‐Wojnilowicz… - Advanced …, 2021 - Wiley Online Library
Bio–nanoscience research encompasses studies on the interactions of nanomaterials with
biological structures or what is commonly referred to as the biointerface. Fundamental …
biological structures or what is commonly referred to as the biointerface. Fundamental …
Molecular imaging of innate immunity and immunotherapy
The innate immune system plays a key role as the first line of defense in various human
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …