Executive summary The 2024 update of the Lancet Commission on dementia provides new
hopeful evidence about dementia prevention, intervention, and care. As people live longer …

Key Points Frailty in Older Adults Assessing frailty enables clinicians to predict the outcomes
and risks of health conditions, target the delivery of evidence-based interventions, and tailor …

Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …

Poor oral health is common among older adults and can impair essential activities of daily
living and contribute to frailty. We did a systematic review of studies on the relationship …

The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Frailty is a syndrome of growing importance given the global ageing population. While frailty
is a multifactorial process, poor nutritional status is considered a key contributor to its …

Frailty is a common condition in older people. The epidemiological data available, however,
are mainly based on the physical frailty phenotype. An extensive literature has suggested …

Frailty is a clinical syndrome characterized by a reduced physiologic reserve, increased
vulnerability to stressors and an increased risk of adverse outcomes. People with atrial …

Frailty is an age-related clinical condition characterised by an increased susceptibility to
stressors and an elevated risk of adverse outcomes such as mortality. In the light of global …

There is an increasing proportion of the general population surviving to old age with
significant chronic disease, multi-morbidity, and disability. The prevalence of pre-frail state …