Microfluidics for drug development: from synthesis to evaluation
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …
delivery, and drug evaluation. Compared with conventional drug development procedures …
PDMS microfabrication and design for microfluidics and sustainable energy application
L Lin, CK Chung - Micromachines, 2021 - mdpi.com
The polydimethylsiloxane (PDMS) is popular for wide application in various fields of
microfluidics, microneedles, biology, medicine, chemistry, optics, electronics, architecture …
microfluidics, microneedles, biology, medicine, chemistry, optics, electronics, architecture …
Nanobubbles for therapeutic delivery: Production, stability and current prospects
Nanobubbles (NBs) have recently garnered widespread attention for their potential use as
dual diagnostic and therapeutic agents. Similar to their micron-sized relatives …
dual diagnostic and therapeutic agents. Similar to their micron-sized relatives …
Advances on colorectal cancer 3D models: The needed translational technology for nanomedicine screening
Colorectal cancer (CRC) is a heterogeneous and molecularly complex disease, associated
with high mortality worldwide, exposing the urgent need for novel therapeutic approaches …
with high mortality worldwide, exposing the urgent need for novel therapeutic approaches …
[HTML][HTML] Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting …
Most cancer patients receive chemotherapy at some stage of their treatment which makes
improving the efficacy of cytotoxic drugs an ongoing and important goal. Despite large …
improving the efficacy of cytotoxic drugs an ongoing and important goal. Despite large …
The influence of nanobubble size and stability on ultrasound enhanced drug delivery
Lipid-shelled nanobubbles (NBs) are emerging as potential dual diagnostic and therapeutic
agents. Similar to their micron-scale counterparts, microbubbles (1–10 μm), they can act as …
agents. Similar to their micron-scale counterparts, microbubbles (1–10 μm), they can act as …
[HTML][HTML] Fluid flow to mimic organ function in 3D in vitro models
Many different strategies can be found in the literature to model organ physiology, tissue
functionality, and disease in vitro; however, most of these models lack the physiological fluid …
functionality, and disease in vitro; however, most of these models lack the physiological fluid …
3D cell models for organ-on-a-chip applications
A Żuchowska, P Baranowska, M Flont, Z Brzózka… - Analytica Chimica …, 2024 - Elsevier
Abstract Two-dimensional (2D) cultures do not fully reflect the human organs' physiology
and the real effectiveness of the used therapy. Therefore, three-dimensional (3D) models …
and the real effectiveness of the used therapy. Therefore, three-dimensional (3D) models …
Microphysiological systems to study colorectal cancer: state-of-the-art
P Ramos, MR Carvalho, W Chen, LP Yan… - …, 2023 - iopscience.iop.org
Basic pre-clinical research based on 2D cultures have been very valuable in colorectal
cancer (CRC) research but still have failed to improve patient prognostic outcomes. This is …
cancer (CRC) research but still have failed to improve patient prognostic outcomes. This is …
[HTML][HTML] Horizon: Microfluidic platform for the production of therapeutic microbubbles and nanobubbles
RH Abou-Saleh, FJ Armistead… - Review of Scientific …, 2021 - pubs.aip.org
Microbubbles (MBs) have a multitude of applications including as contrast agents in
ultrasound imaging and as therapeutic drug delivery vehicles, with further scope for …
ultrasound imaging and as therapeutic drug delivery vehicles, with further scope for …