Anticancer potential of curcumin-cyclodextrin complexes and their pharmacokinetic properties

M Shahriari, P Kesharwani, TP Johnston… - International Journal of …, 2023 - Elsevier
Cancer is one of the most common diseases throughout the world, with many treatment
modalities currently being used, and new treatment strategies being sought. Most …

[HTML][HTML] Therapeutic potential and limitations of curcumin as antimetastatic agent

P Dytrych, Z Kejík, J Hajduch, R Kaplánek… - Biomedicine & …, 2023 - Elsevier
Abstract Treatment of metastatic cancer is one of the biggest challenges in anticancer
therapy. Curcumin is interesting nature polyphenolic compound with unique biological and …

Investigating the targeting power to brain tissues of intranasal rasagiline mesylate-loaded transferosomal in situ gel for efficient treatment of Parkinson's disease

HN ElShagea, RR Makar, AH Salama, NA Elkasabgy… - Pharmaceutics, 2023 - mdpi.com
Rasagiline mesylate (RSM) is a hydrophilic drug with poor oral bioavailability (36%)
because of hepatic first-pass metabolism. The present study focuses on delivering RSM …

Intranasal zolmitriptan-loaded bilosomes with extended nasal mucociliary transit time for direct nose to brain delivery

MM El Taweel, MH Aboul-Einien, MA Kassem… - Pharmaceutics, 2021 - mdpi.com
This study aimed at delivering intranasal zolmitriptan directly to the brain through
preparation of bilosomes incorporated into a mucoadhesive in situ gel with extended nasal …

Merits and advances of microfluidics in the pharmaceutical field: design technologies and future prospects

A Maged, R Abdelbaset, AA Mahmoud… - Drug delivery, 2022 - Taylor & Francis
Microfluidics is used to manipulate fluid flow in micro-channels to fabricate drug delivery
vesicles in a uniform tunable size. Thanks to their designs, microfluidic technology provides …

Therapeutic applications of curcumin nanomedicine formulations in cystic fibrosis

C Quispe, J Herrera-Bravo, K Khan, Z Javed… - Progress in …, 2022 - Springer
Medicinal applications of turmeric-derived curcumin have been known to mankind for long
ages. Its potential in managing “cystic fibrosis” has also been evaluated. This autosomal …

Lipid nanocarrier-based drug delivery systems: therapeutic advances in the treatment of lung cancer

SJ Kim, N Puranik, D Yadav, JO Jin… - International Journal of …, 2023 - Taylor & Francis
Although various treatments are currently being developed, lung cancer still has a very high
mortality rate. Moreover, while various strategies for the diagnosis and treatment of lung …

Novel bioactive extraction and nano-encapsulation

S Noore, NK Rastogi, C O'Donnell, B Tiwari - Encyclopedia, 2021 - mdpi.com
Definition An extraction technology works on the principle of two consecutive steps that
involves mixture of solute with solvent and the movement of soluble compounds from the cell …

Liposomes or extracellular vesicles: a comprehensive comparison of both lipid bilayer vesicles for pulmonary drug delivery

A Al-Jipouri, SH Almurisi, K Al-Japairai, LM Bakar… - Polymers, 2023 - mdpi.com
The rapid and non-invasive pulmonary drug delivery (PDD) has attracted great attention
compared to the other routes. However, nanoparticle platforms, like liposomes (LPs) and …

Different curcumin-loaded delivery systems for wound healing applications: A comprehensive review

SA Sideek, HB El-Nassan, AR Fares, AN ElMeshad… - Pharmaceutics, 2022 - mdpi.com
Curcumin or turmeric is the active constituent of Curcuma longa L. It has marvelous
medicinal applications in many diseases. When the skin integrity is compromised due to …