Cerebellar cortical organization: a one-map hypothesis
R Apps, R Hawkes - Nature Reviews Neuroscience, 2009 - nature.com
The fundamental architecture of the cerebellum is concealed within a terminological forest—
transverse zones and stripes, longitudinal zones and microzones, patches, etc. To make …
transverse zones and stripes, longitudinal zones and microzones, patches, etc. To make …
Genetic regulation of cerebellar development
VY Wang, HY Zoghbi - Nature Reviews Neuroscience, 2001 - nature.com
The cerebellum is one of the first brain structures to begin to differentiate, yet it is one of the
last to achieve maturity—the cellular organization of the cerebellum continues to change for …
last to achieve maturity—the cellular organization of the cerebellum continues to change for …
Morphology, molecular codes, and circuitry produce the three-dimensional complexity of the cerebellum
RV Sillitoe, AL Joyner - Annu. Rev. Cell Dev. Biol., 2007 - annualreviews.org
The most noticeable morphological feature of the cerebellum is its folded appearance,
whereby fissures separate its anterior-posterior extent into lobules. Each lobule is …
whereby fissures separate its anterior-posterior extent into lobules. Each lobule is …
Cellular and genetic regulation of the development of the cerebellar system
C Sotelo - Progress in neurobiology, 2004 - Elsevier
Recent advances in molecular biology have drastically changed our vision on the
development of the nervous system, the cerebellum in particular. After a classical descriptive …
development of the nervous system, the cerebellum in particular. After a classical descriptive …
p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment
J Ko, S Humbert, RT Bronson, S Takahashi… - Journal of …, 2001 - Soc Neuroscience
Cyclin-dependent kinase 5 (Cdk5) plays a pivotal role in brain development and neuronal
migration. Cdk5 is abundant in postmitotic, terminally differentiated neurons. The ability of …
migration. Cdk5 is abundant in postmitotic, terminally differentiated neurons. The ability of …
Cre recombinase expression in cerebellar Purkinje cells
JJ Barski, K Dethleffsen, M Meyer - genesis, 2000 - Wiley Online Library
The cerebellar cortex and its sole output, the Purkinje cell, have been implicated in motor
coordination, learning and cognitive functions. Therefore, the ability to generate Purkinje cell …
coordination, learning and cognitive functions. Therefore, the ability to generate Purkinje cell …
Insights into cerebellar development and connectivity
J Beckinghausen, RV Sillitoe - Neuroscience letters, 2019 - Elsevier
The cerebellum has a well-established role in controlling motor functions such coordination,
balance, posture, and skilled learning. There is mounting evidence that it might also play a …
balance, posture, and skilled learning. There is mounting evidence that it might also play a …
Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorder
N Gharani, R Benayed, V Mancuso… - Molecular …, 2004 - nature.com
Mouse mutants of the homeobox transcription factor Engrailed2 (En2) and autistic
individuals display similar cerebellar morphological abnormalities, which include hypoplasia …
individuals display similar cerebellar morphological abnormalities, which include hypoplasia …
Recent advances in the genetics of autism
AR Gupta, MW State - Biological psychiatry, 2007 - Elsevier
Autism is a strongly genetic disorder, with an estimated heritability of greater than 90%.
Nonetheless, its specific genetic etiology remains largely unknown. Over the past several …
Nonetheless, its specific genetic etiology remains largely unknown. Over the past several …
Development of the cerebellum: from gene expression patterns to circuit maps
JJ White, RV Sillitoe - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
The internal structure of the cerebellum reflects an intriguing paradox; its cytoarchitecture is
relatively simple and repeated throughout, yet the connections between its neurons are …
relatively simple and repeated throughout, yet the connections between its neurons are …