The fundamental architecture of the cerebellum is concealed within a terminological forest—
transverse zones and stripes, longitudinal zones and microzones, patches, etc. To make …

The cerebellum is one of the first brain structures to begin to differentiate, yet it is one of the
last to achieve maturity—the cellular organization of the cerebellum continues to change for …

The most noticeable morphological feature of the cerebellum is its folded appearance,
whereby fissures separate its anterior-posterior extent into lobules. Each lobule is …

Recent advances in molecular biology have drastically changed our vision on the
development of the nervous system, the cerebellum in particular. After a classical descriptive …

Cyclin-dependent kinase 5 (Cdk5) plays a pivotal role in brain development and neuronal
migration. Cdk5 is abundant in postmitotic, terminally differentiated neurons. The ability of …

The cerebellar cortex and its sole output, the Purkinje cell, have been implicated in motor
coordination, learning and cognitive functions. Therefore, the ability to generate Purkinje cell …

The cerebellum has a well-established role in controlling motor functions such coordination,
balance, posture, and skilled learning. There is mounting evidence that it might also play a …

Mouse mutants of the homeobox transcription factor Engrailed2 (En2) and autistic
individuals display similar cerebellar morphological abnormalities, which include hypoplasia …

Autism is a strongly genetic disorder, with an estimated heritability of greater than 90%.
Nonetheless, its specific genetic etiology remains largely unknown. Over the past several …

The internal structure of the cerebellum reflects an intriguing paradox; its cytoarchitecture is
relatively simple and repeated throughout, yet the connections between its neurons are …