Vascular calcification—new insights into its mechanism
Vascular calcification (VC), which is categorized by intimal and medial calcification,
depending on the site (s) involved within the vessel, is closely related to cardiovascular …
depending on the site (s) involved within the vessel, is closely related to cardiovascular …
Endothelial to mesenchymal transition in health and disease
Y Xu, JC Kovacic - Annual Review of Physiology, 2023 - annualreviews.org
The endothelium is one of the largest organ systems in the body, and data continue to
emerge regarding the importance of endothelial cell (EC) dysfunction in vascular aging and …
emerge regarding the importance of endothelial cell (EC) dysfunction in vascular aging and …
TGF-β-induced endothelial to mesenchymal transition in disease and tissue engineering
J Ma, G Sanchez-Duffhues, MJ Goumans… - Frontiers in cell and …, 2020 - frontiersin.org
Endothelial to mesenchymal transition (EndMT) is a complex biological process that gives
rise to cells with multipotent potential. EndMT is essential for the formation of the …
rise to cells with multipotent potential. EndMT is essential for the formation of the …
Signaling pathways in vascular function and hypertension: molecular mechanisms and therapeutic interventions
J Ma, Y Li, X Yang, K Liu, X Zhang, X Zuo… - Signal transduction and …, 2023 - nature.com
Hypertension is a global public health issue and the leading cause of premature death in
humans. Despite more than a century of research, hypertension remains difficult to cure due …
humans. Despite more than a century of research, hypertension remains difficult to cure due …
Associations between systemic immune-inflammation index and abdominal aortic calcification: results of a nationwide survey
Abstract Background and aim The Systemic Immune-Inflammation Index (SII) is a novel
index of inflammation assessment that appears to be superior to the common single blood …
index of inflammation assessment that appears to be superior to the common single blood …
Emerging roles of inflammation-mediated endothelial–mesenchymal transition in health and disease
Y Yoshimatsu, T Watabe - Inflammation and Regeneration, 2022 - Springer
Abstract Endothelial–mesenchymal transition (EndoMT), a cellular differentiation process in
which endothelial cells (ECs) lose their properties and differentiate into mesenchymal cells …
which endothelial cells (ECs) lose their properties and differentiate into mesenchymal cells …
TNF‐α enhances TGF‐β‐induced endothelial‐to‐mesenchymal transition via TGF‐β signal augmentation
Y Yoshimatsu, I Wakabayashi, S Kimuro… - Cancer …, 2020 - Wiley Online Library
The tumor microenvironment (TME) consists of various components including cancer cells,
tumor vessels, cancer‐associated fibroblasts (CAFs), and inflammatory cells. These …
tumor vessels, cancer‐associated fibroblasts (CAFs), and inflammatory cells. These …
The role of bone morphogenetic protein signaling in vascular calcification
P Yang, L Troncone, ZM Augur, SSJ Kim, ME McNeil… - Bone, 2020 - Elsevier
Vascular calcification is associated with atherosclerosis, chronic kidney disease, and
diabetes, and results from processes resembling endochondral or intramembranous …
diabetes, and results from processes resembling endochondral or intramembranous …
Pulmonary hypertension: Linking inflammation and pulmonary arterial stiffening
SF Liu, N Nambiar Veetil, Q Li… - Frontiers in …, 2022 - frontiersin.org
Pulmonary hypertension (PH) is a progressive disease that arises from multiple etiologies
and ultimately leads to right heart failure as the predominant cause of morbidity and …
and ultimately leads to right heart failure as the predominant cause of morbidity and …
Research progress of endothelial‐mesenchymal transition in diabetic kidney disease
Y Chen, H Zou, H Lu, H Xiang… - Journal of Cellular and …, 2022 - Wiley Online Library
Renal fibrosis is an important pathological feature of diabetic kidney disease (DKD),
manifested as tubular interstitial fibrosis, tubular atrophy, glomerulosclerosis and damage to …
manifested as tubular interstitial fibrosis, tubular atrophy, glomerulosclerosis and damage to …