The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

COVID-19 vaccine development: milestones, lessons and prospects

M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …

Dynamics of antibody response to BNT162b2 vaccine after six months: a longitudinal prospective study

P Naaber, L Tserel, K Kangro, E Sepp… - The Lancet Regional …, 2021 - thelancet.com
ABSTRACT Background SARS-CoV-2 mRNA vaccines have proven high efficacy, however,
limited data exists on the duration of immune responses and their relation to age and side …

COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection

JP Evans, C Zeng, C Carlin, G Lozanski… - Science Translational …, 2022 - science.org
The waning efficacy of SARS-CoV-2 vaccines, combined with the continued emergence of
variants resistant to vaccine-induced immunity, has reignited debate over the need for …

BNT162b2 vaccination induces durable SARS-CoV-2–specific T cells with a stem cell memory phenotype

G Guerrera, M Picozza, S D'Orso, R Placido… - Science …, 2021 - science.org
Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
effective in preventing hospitalization from severe COVID-19. However, multiple reports of …

Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study

OT Ranzani, MDT Hitchings, M Dorion, TL D'Agostini… - bmj, 2021 - bmj.com
Objective To estimate the effectiveness of the inactivated whole virus vaccine, CoronaVac
(Sinovac Biotech), against symptomatic covid-19 in the elderly population of São Paulo …

[HTML][HTML] Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions

AI Abulsoud, HM El-Husseiny, AA El-Husseiny… - Biomedicine & …, 2023 - Elsevier
COVID-19 is a worldwide pandemic caused by SARS-coronavirus-2 (SARS-CoV-2). Less
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

A Fendler, STC Shepherd, L Au, KA Wilkinson, M Wu… - Nature cancer, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) antiviral response in a pan-tumor immune
monitoring (CAPTURE)(NCT03226886) is a prospective cohort study of COVID-19 immunity …

Population antibody responses following COVID-19 vaccination in 212,102 individuals

H Ward, M Whitaker, B Flower, SN Tang… - Nature …, 2022 - nature.com
Population antibody surveillance helps track immune responses to COVID-19 vaccinations
at scale, and identify host factors that may affect antibody production. We analyse data from …