Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu… - Chinese chemical …, 2023 - Elsevier
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

Polyphenols as antitumor agents targeting key players in cancer-driving signaling pathways

MH Cháirez-Ramírez, KG de la Cruz-López… - Frontiers in …, 2021 - frontiersin.org
Polyphenols constitute an important group of natural products that are traditionally
associated with a wide range of bioactivities. These are usually found in low concentrations …

Evolution of drug delivery systems: From 1950 to 2020 and beyond

H Park, A Otte, K Park - Journal of Controlled Release, 2022 - Elsevier
Modern drug delivery technology began in 1952 with the advent of the Spansule® sustained-
release capsule technology, which can deliver a drug for 12 h after oral administration …

Revisiting supersaturation of a biopharmaceutical classification system IIB drug: Evaluation via a multi-cup dissolution approach and molecular dynamic simulation

Y Gan, Y Xu, X Zhang, H Hu, W Xiao, Z Yu, T Sun… - Molecules, 2023 - mdpi.com
As a subclass of the biopharmaceutical classification system (BCS) class II, basic drugs
(BCS IIB) exhibit pH-dependent solubility and tend to generate supersaturation in the …

Harnessing artificial intelligence for the next generation of 3D printed medicines

M Elbadawi, LE McCoubrey, FKH Gavins… - Advanced Drug Delivery …, 2021 - Elsevier
Artificial intelligence (AI) is redefining how we exist in the world. In almost every sector of
society, AI is performing tasks with super-human speed and intellect; from the prediction of …

Encapsulation of microalgal-based carotenoids: recent advances in stability and food applications

I Hamed, M Moradi, P Ezati, L O'Higgins… - Trends in food science & …, 2023 - Elsevier
Background Carotenoids are among the most important pigments found in nature, which are
synthesized by various eukaryotic and prokaryotic organisms. With few knows exceptions …

Let's talk about sex: Differences in drug therapy in males and females

CM Madla, FKH Gavins, HA Merchant, M Orlu… - Advanced drug delivery …, 2021 - Elsevier
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …

Static in vitro digestion model adapted to the general older adult population: an INFOGEST international consensus

O Ménard, U Lesmes, CS Shani-Levi, AA Calahorra… - Food & Function, 2023 - pubs.rsc.org
Understanding the mechanisms of food digestion is of paramount importance to determine
the effect foods have on human health. Significant knowledge on the fate of food during …

Potential roles of gut microbes in biotransformation of natural products: An overview

Y Zhao, X Zhong, J Yan, C Sun, X Zhao… - Frontiers in …, 2022 - frontiersin.org
Natural products have been extensively applied in clinical practice, characterized by multi-
component and multi-target, many pharmacodynamic substances, complex action …

Self‐thermophoretic nanoparticles enhance intestinal mucus penetration and reduce pathogenic bacteria interception in colorectal cancer

ZH Wang, W Huang, S Zhang, M Chu… - Advanced Functional …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is the second most common cause of cancer incidence worldwide.
Oral drug delivery systems (ODDS) have shown great promise for CRC therapy, but the …