Ocular in situ gel: An overview

A Majeed, NA Khan - Journal of Drug Delivery and Therapeutics, 2019 - jddtonline.info
Eye is the most sensitive organ of the body. Designing of ocular drug delivery system is the
most challenging field for pharmaceutical scientists as less than 5% of administered drug …

The Effect of Polymers on Drug Release Kinetics in Nanoemulsion In Situ Gel Formulation

KR Vijaya Rani, S Rajan, M Bhupathyraaj, RK Priya… - Polymers, 2022 - mdpi.com
Glaucoma is an ocular condition characterized by elevated intraocular pressure (IOP).
Conventional treatments of glaucoma face poor corneal permeability and bioavailability. To …

Natural polymer Effect on gelation and rheology of ketotifen-loaded pH-sensitive in situ ocular gel (Carbapol)

ZA Sadeq, LA Sabri, KK Al-Kinani - Journal of Advanced Pharmacy …, 2022 - japer.in
In situ gel can be defined as a polymer solution administered as a liquid and when exposed
to some physiologic condition such as the pH, ionic, temperature modulation or solvent and …

Ocular Novel Formulations: Current Impact and Future Challenges.

TL SHARMA, A BASNETT… - International …, 2023 - search.ebscohost.com
Human eyes, the most sensitive and vital organ of human body, comprise of various ocular
barriers that makes it very challenging for the formulating scientist to develop and design …

Formulation and Evaluation of ocular in-Situ gelling system containing ciprofloxacin and Naproxen Sodium

ZA Al-Juboori, ZH Mahdi… - Research Journal of …, 2021 - indianjournals.com
Ocular drug delivery was considered a challenging approach for many decades, due to the
limitation in the bioavailability in addition to the common drawbacks of the conventional eye …

[PDF][PDF] In situ opthalmic gel with ion activated system

IS Kurniawansyah, T Rusdiana, HA Wahab… - International Journal of …, 2019 - academia.edu
In situ gel with ion activated system which occurs as triggered by a change in the ionic
strength. Osmotic gradient is a factor that determines the rate of gelation on the surface of …

[PDF][PDF] Formulation and evaluation of flurbiprofen ocular in-situ gel

SK Aligeti, RK Jampala, J Vinaya - Int. J. Pharm. Sci. Res, 2018 - researchgate.net
Conventional ophthalmic preparations exhibit poor bioavailability due to the rapid
precorneal elimination of the drug, and the physiological constraints imposed by the …

IN-SITU GELLING SYSTEM: AN ALTERNATIVE CONTENDER FOR CONVENTIONAL DRUG DELIVERY

V Maury, K Kushwaha, P Katiyar, H Gautam… - Zibaldone Estudios …, 2024 - zibaldone.cfd
The oral route is among the most often utilized methods for drug delivery however it usually
presents the disadvantage of reduced bioavailability due to the first-pass metabolism. Many …

[PDF][PDF] 1Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India

A Chowdhury, S Mandal - bcrcppharmawave.net
A series of progressive visual neuropathies known as glaucoma are defined by alterations in
the optic nerve head as a result of retinal ganglion cell degeneration. It often happens when …

Review article on in-situ of ocular drug delivery system

P Venkatesh - International Journal of Health Care and …, 2022 - saapjournals.org
Ocular drug delivery is the most challenging and interesting field in the pharmaceutical
industry and pharmaceutical scientist. Blindness and vision impairment are the most …