Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous
concern in every transplantation proceeding, from whole organs to modest grafts. Given its …

Inflammation and oxidative stress are the main pathological processes that accompany
ischemic injury of kidneys and other organs. Based on this, these factors are often chosen as …

Cadmium (Cd) is a serious environmental and occupational contaminant that represents a
serious health hazard to humans and other animals. Reproductive health problems have …

Insulin resistance (IR) has emerged as one of the main risk factors for renal fibrosis (RF) that
represents a common stage in almost all chronic kidney disease. The present study aims to …

Purpose: This experimental study was designed to explore the protective effect of apocynin,
the NADPH-oxidase inhibitor, on kidney damage induced by ischemia/reperfusion (I/R) in a …

Traumatic brain injury (TBI) has both high morbidity and mortality rates and can negatively
influence physical and mental health, while also causing extreme burden to both individual …

The release of inflammatory cytokines, namely tumor necrosis factor‐α (TNF‐α), plays an
important role in the pathogenesis of cardiomyopathy. TNF‐α increases in plasma and in …

Background As organ shortage is increasing, the acceptance of marginal donors increases,
which might result in poor organ function and patient survival. Mostly, organ damage is …

Materials and Methods. We administered methotrexate at a dose of 20 mg/kg as a single
intraperitoneal injection in 10 rats (methotrexate group). Another group of 10 rats received a …

Abstract Kidney injury molecule-1 (KIM-1) staining has been shown to be very useful in
identifying acute proximal tubular injury, but its sensitivity, specificity and predicting values …