Use of biodegradable polymers for biomedical applications has increased in recent decades
due to their biocompatibility, biodegradability, flexibility, and minimal side effects …

Clathrin is best known for its contribution to clathrin-mediated endocytosis yet it also
participates to a diverse range of cellular functions. Key to this is clathrin's ability to …

Background Gastric cancer remains the second leading cause of cancer-related deaths in
the world. Successful early gastric cancer detection is hampered by lack of highly sensitive …

Biological membranes constitute boundaries of cells and cell organelles. These membranes
are soft fluid interfaces whose thermodynamic states are dictated by bending moduli …

Phagocytosis is a fascinating process whereby a cell surrounds and engulfs particles such
as bacteria and dead cells. This is crucial both for single-cell organisms (as a way of …

Highlights•CPPs can partake in multiple cellular uptake mechanisms.•MD simulations can
be used to gain atomistic insight into CPP uptake mechanisms.•Biomolecular MD …

Most viruses take advantage of endocytic pathways to gain entry into host cells and initiate
infections. Understanding of virus entry via endocytosis is critically important for the design …

Novel Alzheimer's disease (AD) risk factors have been identified by genome-wide
association studies. Elucidating the mechanism underlying these factors is critical to the …

Phosphoinositides are membrane lipids generated by phosphorylation on the inositol head
group of phosphatidylinositol. By specifically distributed to distinct subcellular membrane …

Endocytosis is a mechanism that internalizes and recycles plasma membrane components
and transmembrane receptors via vesicle formation, which is mediated by clathrin …