While multiple theories have been put forth regarding the origin of schizophrenia, by far the
vast majority of evidence points to the neurodevelopmental model in which developmental …

Reelin is a glycoprotein that serves important roles both during development (regulation of
neuronal migration and brain lamination) and in adulthood (maintenance of synaptic …

In this article, we review studies detailing the correspondence between peripheral blood and
brain tissue across various domains of high‐throughput‐omic analysis in order to provide a …

The term “Epigenetics” refers to DNA and chromatin modifications that persist from one cell
division to the next, despite a lack of change in the underlying DNA sequence. The …

The last decade of research into the pharmacogenetics of antipsychotics has seen the
development of genetic tests to determine the patients' metabolic status and the first attempts …

Prenatal viral infection has been associated with development of schizophrenia and autism.
Our laboratory has previously shown that viral infection causes deleterious effects on brain …

The consistency of peripheral gene expression data and the overlap with brain expression
has not been evaluated in biomarker discovery, nor has it been reported in multiple tissues …

Emerging researches point to a relevant role of postsynaptic density (PSD) proteins, such as
PSD-95, Homer, Shank, and DISC-1, in the pathophysiology of schizophrenia and autism …

Alterations in synaptic signaling and plasticity occur during the refinement of neural circuits
over the course of development and the adult processes of learning and memory. Synaptic …

Several lines of evidence indicate that dysfunction of serotonin signaling and HTR2A
receptor are involved in the pathogenesis of schizophrenia (SCZ) and bipolar disorder (BD) …