Nectins and nectin-like molecules (Necls) are immunoglobulin-like transmembrane cell
adhesion molecules that are expressed in various cell types. Homophilic and heterophilic …

Abstract Poliovirus receptor (PVR, CD155) has recently been gaining scientific interest as a
therapeutic target in the field of tumor immunology due to its prominent endogenous and …

CD 155 is the fifth member in the nectin‐like molecule family, and functions as the receptor
of poliovirus; therefore, CD 155 is also referred to as necl‐5, or PVR. As an immunoglobulin …

Abstract CD155 (PVR/necl5/Tage4), a member of the nectin-like family of adhesion
molecules, is highly upregulated on tumor cells across multiple cancer types and has been …

Nectins are immunoglobulin-like cell adhesion molecules (CAMs) that compose a family of
four members. Nectins homophilically and heterophilically interact in trans with each other to …

Macrophage death in advanced atherosclerosis promotes necrosis and plaque
destabilization. A likely cause of macrophage death is accumulation of free cholesterol (FC) …

Nectins (nectin1–4) and Necls [nectin-like (Necl1–5)] are Ig superfamily cell adhesion
molecules that regulate cell differentiation and tissue morphogenesis. Adherens junction …

The regulation of metabolism and growth must be tightly coupled to guarantee the efficient
use of energy and anabolic substrates throughout the cell cycle. Fructose 2, 6-bisphosphate …

In recent years, there have been multiple breakthroughs in cancer immunotherapy, with
immune checkpoint inhibitors becoming the most promising treatment strategy. However …

Background/Aim: CD155 is expressed in many types of human cells and has diverse
functions. We herein evaluated the cli ni cal importance of CD155 in pancreatic cancer …