Lipids play crucial roles in signal transduction, contribute to the structural integrity of cellular
membranes, and regulate energy metabolism. Questions remain as to which lipid species …

Podocytopathies are kidney diseases in which direct or indirect podocyte injury drives
proteinuria or nephrotic syndrome. In children and young adults, genetic variants in> 50 …

Circulating blood is filtered across the glomerular barrier to form an ultrafiltrate of plasma in
the Bowman's space. The volume of glomerular filtration adjusted by time is defined as the …

Objective: To identify factors that contribute to the increased susceptibility and severity of
COVID-19 in obese children and adolescents, and its health consequences. Sources …

Excessive adiposity raises blood pressure and accounts for 65–75% of primary
hypertension, which is a major driver of cardiovascular and kidney diseases. In obesity …

Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural
abnormalities or impaired excretory renal function suggestive of a loss of functional …

More than one-third of the worldwide population is overweight or obese and therefore at risk
of developing type 2 diabetes mellitus. In order to mitigate this pandemic, safer and more …

The increasing global prevalence of type 2 diabetes mellitus (T2DM) and chronic kidney
disease (CKD) has prompted research efforts to tackle the growing epidemic of diabetic …

Cellular lipid metabolism and homeostasis are controlled by sterol regulatory-element
binding proteins (SREBPs). In addition to performing canonical functions in the …

Obesity is now a worldwide epidemic ensuing an increase in comorbidities' prevalence,
such as insulin resistance, type 2 diabetes (T2D), metabolic dysfunction-associated fatty …