The renaissance of α‐methylene‐γ‐butyrolactones: new synthetic approaches

RRA Kitson, A Millemaggi… - Angewandte Chemie …, 2009 - Wiley Online Library
The amount of research activity concerning α‐methylene‐γ‐butyrolactones and α‐alkylidene‐
γ‐butyrolactones has increased dramatically in recent years. This Review summarizes the …

Recent advances in the synthesis of α‐alkylidene‐substituted δ‐lactones, γ‐lactams and δ‐lactams

A Albrecht, Ł Albrecht, T Janecki - European Journal of Organic …, 2011 - Wiley Online Library
Abstract α‐Alkylidene‐substituted δ‐lactones and corresponding γ‐and δ‐lactams constitute
important classes of natural compounds that display diverse biological activities. This review …

Highly Efficient C H Hydroxylation of Carbonyl Compounds with Oxygen under Mild Conditions

YF Liang, N Jiao - Angewandte Chemie International Edition, 2014 - Wiley Online Library
A transition‐metal‐free Cs2CO3‐catalyzed α‐hydroxylation of carbonyl compounds with O2
as the oxygen source is described. This reaction provides an efficient approach to tertiary α …

Synthesis of sulfonylated lactones via Ag-catalyzed cascade sulfonylation/cyclization of 1, 6-enynes with sodium sulfinates

W Wu, S Yi, Y Yu, W Huang, H Jiang - The Journal of Organic …, 2017 - ACS Publications
A novel strategy for the synthesis of sulfonylated lactones via Ag-catalyzed radical
addition/cyclization reaction of 1, 6-enynes and sodium sulfinates has been developed. The …

Oxindole synthesis by direct C–H, Ar–H coupling

A Perry, RJK Taylor - Chemical communications, 2009 - pubs.rsc.org
Oxindole synthesis by direct C–H, Ar–H coupling - Chemical Communications (RSC Publishing)
DOI:10.1039/B903516H Royal Society of Chemistry View PDF VersionPrevious ArticleNext …

A thiol-mediated three-step ring expansion cascade for the conversion of indoles into functionalized quinolines

N Inprung, MJ James, RJK Taylor, WP Unsworth - Organic letters, 2021 - ACS Publications
An operationally simple, high yielding three-step cascade process is described for the direct
conversion of indole-tethered ynones into functionalized quinolines. A single “multitasking” …

Bu4NI-Catalyzed α-Oxyacylation of Carbonyl Compounds with Toluene Derivatives

C Li, T Jin, X Zhang, C Li, X Jia, J Li - Organic letters, 2016 - ACS Publications
A TBAI (tetrabutylammonium iodide)-catalyzed direct α-oxyacylation of carbonyl compounds
from readily available toluene derivatives has been developed. The distinguished features …

Biomacromolecule-Assisted Screening for Reaction Discovery and Catalyst Optimization

SM Ramos De Dios, VK Tiwari, CD McCune… - Chemical …, 2022 - ACS Publications
Reaction discovery and catalyst screening lie at the heart of synthetic organic chemistry.
While there are efforts at de novo catalyst design using computation/artificial intelligence, at …

Propanephosphonic acid anhydride (T3P®)-A benign reagent for diverse applications inclusive of large-scale synthesis

TM Vishwanatha, NR Panguluri, VV Sureshbabu - Synthesis, 2013 - thieme-connect.com
Propanephosphonic acid anhydride (T3P®) is a prevailing coupling and dehydrating agent
with many desirable properties which render it a reagent of choice for a plethora of reactions …

Ru (ii)-catalyzed cascade cis carbohalogenation and cyclization of alkyne-tethered cyclohexadienones for synthesizing tetrasubstituted alkenes

X Huang, C Yi, R Xiong, M Bai, Y Tang… - Organic Chemistry …, 2024 - pubs.rsc.org
We have established an efficient ruthenium (II)-catalyzed cis carbohalogenation and
carbooxygenation cyclization of internal alkyne-tethered cyclohexadienones with halide and …