Platelets play a central role in hemostasis, but also in atherothrombosis, as they rapidly
adhere to tissue and to one another as a response to any vascular injury. This process …

After a decade of the “modern era” of zebrafish hematology research, what have been their
major contributions to hematology and what challenges does the model face? This review …

Clinical studies and animal experimentation have shown that colonic inflammation is
associated with an increased number and reactivity of platelets, coagulation abnormalities …

Hemostasis is a function of paramount importance when an animal is responding to an
injury or has a blood coagulation disorder. It is important to stop the bleeding after a vascular …

Thrombosis is a leading cause of morbidity and mortality worldwide. Animal models are
used to understand the pathological pathways involved in thrombosis and to test the efficacy …

Background Platelets circulate in the blood of healthy individuals for approximately 7–10
days regulated by finely balanced processes of production and destruction. As platelets are …

Platelet ageing is an area of research which has gained much interest in recent years.
Newly formed platelets, often referred to as reticulated platelets, young platelets or immature …

Within the healthy population, there is substantial, heritable, and interindividual variability in
the platelet response. We explored whether a proportion of this variability could be …

The platelet plasma membrane is literally at the cutting-edge of recent research into
proteolytic regulation of the function and surface expression of platelet receptors, revealing …

Objective—The goal of this study was to define and characterize the subpopulation of
platelets capable of regulating the functional interactions of factors Va (FVa) and Xa (FXa) …