Diagnostic morphology: biophysical indicators for iron-driven inflammatory diseases

E Pretorius, DB Kell - Integrative biology, 2014 - academic.oup.com
Most non-communicable diseases involve inflammatory changes in one or more vascular
systems, and there is considerable evidence that unliganded iron plays major roles in this …

[HTML][HTML] The IRONy in Athletic Performance

W Kardasis, ER Naquin, R Garg, T Arun, JS Gopianand… - Nutrients, 2023 - mdpi.com
Iron is an essential micronutrient for athletes, intricately linked to their performance, by
regulating cellular respiration and metabolism. Impaired iron levels in the body can …

[HTML][HTML] Histology, staining

TS Gurina, L Simms - 2020 - europepmc.org
Medical Histology is the microscopic study of tissues and organs through sectioning,
staining, and examining those sections under a microscope. Often called microscopic …

[HTML][HTML] Profound morphological changes in the erythrocytes and fibrin networks of patients with hemochromatosis or with hyperferritinemia, and their normalization by …

E Pretorius, J Bester, N Vermeulen, B Lipinski… - PloS one, 2014 - journals.plos.org
It is well-known that individuals with increased iron levels are more prone to thrombotic
diseases, mainly due to the presence of unliganded iron, and thereby the increased …

Fe2+ block and permeation of CaV3. 1 (α1G) T-type calcium channels: Candidate mechanism for non–transferrin-mediated Fe2+ influx

KV Lopin, IP Gray, CA Obejero-Paz, F Thevenod… - Molecular …, 2012 - ASPET
Iron is a biologically essential metal, but excess iron can cause damage to the
cardiovascular and nervous systems. We examined the effects of extracellular Fe2+ on …

[HTML][HTML] Non-invasive methods for liver fibrosis prediction in hemochromatosis: One step beyond

A Castiella, E Zapata, JM Alústiza - World Journal of Hepatology, 2010 - ncbi.nlm.nih.gov
Advances in recent years in the understanding of, and the genetic diagnosis of hereditary
hemochromatosis (HH) have changed the approach to iron overload hereditary diseases …

Properties of donated red blood cell components from patients with hereditary hemochromatosis

C Sut, H Hamzeh‐Cognasse, S Laradi, V Bost… - …, 2017 - Wiley Online Library
BACKGROUND Red blood cells (RBCs) contain large amounts of iron, and periodic
therapeutic phlebotomy is thus the main treatment for hereditary hemochromatosis (HH) …

Combined use of wild‐type HBV precore and high serum iron marker as a potential tool for the prediction of cirrhosis in chronic Hepatitis B infection

JB Chook, YF Ngeow, SF Yap, TC Tan… - Journal of medical …, 2011 - Wiley Online Library
Hepatitis B virus (HBV) and high liver iron deposits have both been associated with the
development of cirrhosis. Among HBV factors, genotype and mutations in the basal core …

[HTML][HTML] Iranian hereditary hemochromatosis patients: baseline characteristics, laboratory data and gene mutations

F Zamani, Z Bagheri, M Bayat… - … Medical Journal of …, 2012 - ncbi.nlm.nih.gov
Background Hereditary hemochromatosis (HH) is the most common autosomal recessive
disorder in white people, characterized by highly abnormal uptake of iron from the …

Noninvasive Alternatives of Liver Biopsy

K Aiglová - Liver Biopsy, 2011 - books.google.com
Liver biopsy is considered the gold standart for the diagnosis of cirrhosis, it has important
limitations, such as being invasive, having the potential for complications and false-negative …