[HTML][HTML] Diagnostic modalities of non-alcoholic fatty liver disease: from biochemical biomarkers to multi-omics non-invasive approaches

E Martinou, M Pericleous, I Stefanova, V Kaur… - Diagnostics, 2022 - mdpi.com
Non-Alcoholic Fatty Liver Disease (NAFLD) is currently the most common cause of chronic
liver disease worldwide, and its prevalence is increasing globally. NAFLD is a multifaceted …

[HTML][HTML] Diagnostic accuracy of blood biomarkers and non-invasive scores for the diagnosis of NAFLD and NASH: Systematic review and meta-analysis

D Contreras, A González-Rocha, P Clark… - Annals of …, 2023 - Elsevier
Introduction and objectives Fatty liver disease is an important public health problem. Early
diagnosis is critical to lower its rate of progression to irreversible/terminal stages. This study …

[HTML][HTML] Prevalence of non-alcoholic fatty liver disease and risk factors for advanced fibrosis and mortality in the United States

MH Le, P Devaki, NB Ha, DW Jun, HS Te, RC Cheung… - PloS one, 2017 - journals.plos.org
In the United States, non-alcoholic fatty liver disease (NAFLD) is the most common liver
disease and associated with higher mortality according to data from earlier National Health …

Effects of statin use on the development and progression of nonalcoholic fatty liver disease: a nationwide nested case-control study

JI Lee, HW Lee, KS Lee, HS Lee… - Official journal of the …, 2021 - journals.lww.com
METHODS: This study included 11,593,409 subjects from the National Health Information
Database of the Republic of Korea entered in 2010 and followed up until 2016. NAFLD was …

Links between gut microbiome composition and fatty liver disease in a large population sample

MO Ruuskanen, F Åberg, V Männistö, AS Havulinna… - Gut …, 2021 - Taylor & Francis
Fatty liver disease is the most common liver disease in the world. Its connection with the gut
microbiome has been known for at least 80 y, but this association remains mostly unstudied …

Metabolic dysfunction–associated fatty liver disease predicts new onset of chronic kidney disease better than fatty liver or nonalcoholic fatty liver disease

M Tanaka, K Mori, S Takahashi… - Nephrology Dialysis …, 2023 - academic.oup.com
Background Possible associations of chronic kidney disease (CKD) with fatty liver (FL) and
nonalcoholic fatty liver disease (NAFLD) have recently been focused on. Metabolic …

[HTML][HTML] Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting

Y Liu, G Meric, AS Havulinna, SM Teo, F Åberg… - Cell Metabolism, 2022 - cell.com
The gut microbiome has shown promise as a predictive biomarker for various diseases.
However, the potential of gut microbiota for prospective risk prediction of liver disease has …

[HTML][HTML] Effects of fructose restriction on liver steatosis (FRUITLESS); a double-blind randomized controlled trial

N Simons, P Veeraiah, PIHG Simons… - The American journal of …, 2021 - Elsevier
Background There is an ongoing debate on whether fructose plays a role in the
development of nonalcoholic fatty liver disease. Objectives The aim of this study was to …

Ethnic influence on nonalcoholic fatty liver disease prevalence and lack of disease awareness in the United States, 2011–2016

MH Le, YH Yeo, R Cheung, VWS Wong… - Journal of Internal …, 2020 - Wiley Online Library
Background Nonalcoholic fatty liver disease (NAFLD) is a rising global disease associated
with clinical and economic burdens. Objectives We aimed to quantify NAFLD prevalence …

Fatty liver index and development of cardiovascular disease: findings from the UK biobank

B Zou, YH Yeo, R Cheung, E Ingelsson… - Digestive Diseases and …, 2021 - Springer
Background Nonalcoholic fatty liver disease is common and is associated with rising
morbidity and mortality in the UK. Cardiovascular disease is the main cause of death in …