MCNN_MC: Computational Prediction of Mitochondrial Carriers and Investigation of Bongkrekic Acid Toxicity Using Protein Language Models and Convolutional …

MS Malik, YY Chang, YC Liu, VT Le… - Journal of Chemical …, 2024 - ACS Publications
Mitochondrial carriers (MCs) are essential proteins that transport metabolites across
mitochondrial membranes and play a critical role in cellular metabolism. ADP/ATP …

ATP_mCNN: Predicting ATP binding sites through pretrained language models and multi-window neural networks

VT Le, MS Malik, YJ Lin, YC Liu, YY Chang… - Computers in Biology and …, 2025 - Elsevier
Adenosine triphosphate plays a vital role in providing energy and enabling key cellular
processes through interactions with binding proteins. The increasing amount of protein …

mCNN-glucose: Identifying families of glucose transporters using a deep convolutional neural network based on multiple-scanning windows

SMA Shah, M Rafi, MS Malik, SA Malik… - International Journal of …, 2025 - Elsevier
Glucose transporters are essential carrier proteins that function on the phospholipid bilayer
to facilitate glucose diffusion across cell membranes. The transporters play many …

VesiMCNN: Using pre-trained protein language models and multiple window scanning convolutional neural networks to identify vesicular transport proteins

YH Tseng, YC Liu, MS Malik, YY Ou - International Journal of Biological …, 2024 - Elsevier
Vesicular transport is a critical cellular process responsible for the proper organization and
functioning of eukaryotic cells. This mechanism relies on specialized vesicles that shuttle …

DeepPLM_mCNN: An approach for enhancing ion channel and ion transporter recognition by multi-window CNN based on features from pre-trained language models

VT Le, MS Malik, YH Tseng, YC Lee, CI Huang… - … Biology and Chemistry, 2024 - Elsevier
Accurate classification of membrane proteins like ion channels and transporters is critical for
elucidating cellular processes and drug development. We present DeepPLM_mCNN, a …

MCNN-AAPT: accurate classification and functional prediction of amino acid and peptide transporters in secondary active transporters using protein language models …

MS Malik, VT Le, SMA Shah, YY Ou - Journal of Biomolecular …, 2024 - Taylor & Francis
Secondary active transporters play a crucial role in cellular physiology by facilitating the
movement of molecules across cell membranes. Identifying the functional classes of these …

[PDF][PDF] Artificial intelligence and Computer-Aided Drug Discovery: Methods Development and Application

H Zhang, Y Wei, KM Saravanan… - Methods (San Diego …, 2024 - researchgate.net
Artificial intelligence (AI) has become influential in drug discovery, transforming conventional
approaches and enabling novel solutions. Incorporating AI into drug discovery procedures …