Gram‐positive uropathogens, polymicrobial urinary tract infection, and the emerging microbiota of the urinary tract
Uncomplicated urinary‐tract infection (UTI) is most common in young, sexually active,
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …
From in vitro to in vivo Models of Bacterial Biofilm-Related Infections
The influence of microorganisms growing as sessile communities in a large number of
human infections has been extensively studied and recognized for 30–40 years, therefore …
human infections has been extensively studied and recognized for 30–40 years, therefore …
Options and limitations in clinical investigation of bacterial biofilms
M Magana, C Sereti, A Ioannidis… - Clinical Microbiology …, 2018 - Am Soc Microbiol
Bacteria can form single-and multispecies biofilms exhibiting diverse features based upon
the microbial composition of their community and microenvironment. The study of bacterial …
the microbial composition of their community and microenvironment. The study of bacterial …
“It takes a village”: mechanisms underlying antimicrobial recalcitrance of polymicrobial biofilms
G Orazi, GA O'Toole - Journal of Bacteriology, 2019 - Am Soc Microbiol
Chronic infections are frequently caused by polymicrobial biofilms. Importantly, these
infections are often difficult to treat effectively in part due to the recalcitrance of biofilms to …
infections are often difficult to treat effectively in part due to the recalcitrance of biofilms to …
Infection in an aging population
KA Kline, DME Bowdish - Current opinion in microbiology, 2016 - Elsevier
Highlights•One third of deaths in adults in the elderly are due to infectious disease.•Changes
in the aging immune response increase the risk of infection in the elderly.•Respiratory …
in the aging immune response increase the risk of infection in the elderly.•Respiratory …
Spectrum of bacterial colonization associated with urothelial cells from patients with chronic lower urinary tract symptoms
R Khasriya, S Sathiananthamoorthy… - Journal of clinical …, 2013 - Am Soc Microbiol
Chronic lower urinary tract symptoms (LUTS), such as urgency and incontinence, are
common, especially among the elderly, but their etiology is often obscure. Recent studies of …
common, especially among the elderly, but their etiology is often obscure. Recent studies of …
Mechanisms of synergy in polymicrobial infections
Communities of microbes can live almost anywhere and contain many different species.
Interactions between members of these communities often determine the state of the habitat …
Interactions between members of these communities often determine the state of the habitat …
[HTML][HTML] Roles of the vagina and the vaginal microbiota in urinary tract infection: evidence from clinical correlations and experimental models
AL Lewis, NM Gilbert - GMS infectious diseases, 2020 - ncbi.nlm.nih.gov
Mounting evidence indicates that the vagina can harbor uropathogenic bacteria. Here, we
consider three roles played by the vagina and its bacterial inhabitants in urinary tract …
consider three roles played by the vagina and its bacterial inhabitants in urinary tract …
Enzymatic modifications of exopolysaccharides enhance bacterial persistence
Biofilms are surface-attached communities of bacterial cells embedded in a self-produced
matrix that are found ubiquitously in nature. The biofilm matrix is composed of various …
matrix that are found ubiquitously in nature. The biofilm matrix is composed of various …
Transient microbiota exposures activate dormant Escherichia coli infection in the bladder and drive severe outcomes of recurrent disease
NM Gilbert, VP O'Brien, AL Lewis - PLoS pathogens, 2017 - journals.plos.org
Pathogens often inhabit the body asymptomatically, emerging to cause disease in response
to unknown triggers. In the bladder, latent intracellular Escherichia coli reservoirs are …
to unknown triggers. In the bladder, latent intracellular Escherichia coli reservoirs are …