The past decade has seen significant advances in understanding of the pathogenesis and
progression of lung disease in cystic fibrosis (CF). Pulmonary inflammation, infection, and …

Infectious keratitis is a serious cause of vision loss. Proper treatment of infectious keratitis
requires antimicrobials that target the organism responsible for a patient's ulcer. The …

Pseudomonas aeruginosa is commonly found in nosocomial and life‐threatening infections
in patients. Biofilms formed by P. aeruginosa exhibit much greater resistance to antibiotics …

Rationale: Increasing evidence suggests that exposure to ambient air pollution contributes
to the severity of cystic fibrosis (CF) respiratory disease in school-age children and adults; …

Background The cline of human genetic diversity observable across Europe is recapitulated
at a micro-geographic scale by variation within the Italian population. Besides resulting from …

Individuals with cystic fibrosis (CF) suffer from frequent and recurring microbial airway
infections. The Gram-negative bacterium Pseudomonas aeruginosa is one of the most …

Introduction Natural, social, and constructed environments play a critical role in the
development and exacerbation of respiratory diseases. However, less is known regarding …

Background The role of air pollution in increasing susceptibility to respiratory tract infections
in the cystic fibrosis (CF) population has not been well described. We recently demonstrated …

Background Pseudomonas aeruginosa is one of the top three causes of opportunistic
infections in humans. Patients with a compromised immune system, due to …

The biofilm formation of microorganisms causes persistent tissue infections resistant to
treatment with antimicrobial agents. Pseudomonas aeruginosa is commonly isolated from …