Low-intensity ultrasound neuromodulation: an overview of mechanisms and emerging human applications
Background There is an emerging need for noninvasive neuromodulation techniques to
improve patient outcomes while minimizing adverse events and morbidity. Low-intensity …
improve patient outcomes while minimizing adverse events and morbidity. Low-intensity …
Strategies to improve delivery of anticancer drugs across the blood–brain barrier to treat glioblastoma
RK Oberoi, KE Parrish, TT Sio, RK Mittapalli… - Neuro …, 2015 - academic.oup.com
Glioblastoma (GBM) is a lethal and aggressive brain tumor that is resistant to conventional
radiation and cytotoxic chemotherapies. Molecularly targeted agents hold great promise in …
radiation and cytotoxic chemotherapies. Molecularly targeted agents hold great promise in …
Ultrasonic interfacial engineering of red phosphorous–metal for eradicating MRSA infection effectively
Sonodynamic therapy (SDT) is considered to be a potential treatment for various diseases
including cancers and bacterial infections due to its deep penetration ability and biosafety …
including cancers and bacterial infections due to its deep penetration ability and biosafety …
Transcranial magnetic resonance imaging–guided focused ultrasound surgery of brain tumors: initial findings in 3 patients
OBJECTIVE This work evaluated the clinical feasibility of transcranial magnetic resonance
imaging–guided focused ultrasound surgery. METHODS Transcranial magnetic resonance …
imaging–guided focused ultrasound surgery. METHODS Transcranial magnetic resonance …
Systematic examination of low-intensity ultrasound parameters on human motor cortex excitability and behavior
Low-intensity transcranial ultrasound (TUS) can non-invasively modulate human neural
activity. We investigated how different fundamental sonication parameters influence the …
activity. We investigated how different fundamental sonication parameters influence the …
Transcranial magnetic resonance imaging–guided focused ultrasound: noninvasive central lateral thalamotomy for chronic neuropathic pain
D Jeanmonod, B Werner, A Morel, L Michels… - Neurosurgical …, 2012 - thejns.org
Object Recent technological developments open the field of therapeutic application of
focused ultrasound to the brain through the intact cranium. The goal of this study was to …
focused ultrasound to the brain through the intact cranium. The goal of this study was to …
Ultrasonic neuromodulation
O Naor, S Krupa, S Shoham - Journal of neural engineering, 2016 - iopscience.iop.org
Ultrasonic waves can be non-invasively steered and focused into mm-scale regions across
the human body and brain, and their application in generating controlled artificial …
the human body and brain, and their application in generating controlled artificial …
Ultrasound-induced blood-brain barrier opening
Over 4 million US men and women suffer from Alzheimer's disease; 1 million from
Parkinson's disease; 350,000 from multiple sclerosis (MS); and 20,000 from amyotrophic …
Parkinson's disease; 350,000 from multiple sclerosis (MS); and 20,000 from amyotrophic …
Image-guided ultrasound phased arrays are a disruptive technology for non-invasive therapy
Focused ultrasound offers a non-invasive way of depositing acoustic energy deep into the
body, which can be harnessed for a broad spectrum of therapeutic purposes, including …
body, which can be harnessed for a broad spectrum of therapeutic purposes, including …
Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain—a primate study
MRI-guided and monitored focused ultrasound thermal surgery of brain through intact skull
was tested in three rhesus monkeys. The aim of this study was to determine the amount of …
was tested in three rhesus monkeys. The aim of this study was to determine the amount of …