Monocytes (Mo) and macrophages (Mϕ) are key components of the innate immune system
and are involved in regulation of the initiation, development, and resolution of many …

Human blood monocytes are heterogeneous and conventionally subdivided into two
subsets based on CD16 expression. Recently, the official nomenclature subdivides …

Macrophages as innate immune cells and fast responders to antigens play a central role in
protecting the body from the luminal content at a huge interface. Chronic inflammation in …

Monocytes are primitive hematopoietic cells that primarily arise from the bone marrow,
circulate in the peripheral blood and give rise to differentiated macrophages. Over the past …

Monocytes and macrophages are part of the body's first line of defence, eliminating
pathogens by phagocytosis or by releasing a broad array of inflammatory mediators, such as …

Immune regulation by cytokines is crucial in maintaining immune homeostasis, promoting
responses to infection, resolving inflammation, and promoting immunological memory …

Progressive renal failure causes uremia-related immune dysfunction, which features a
chronic inflammatory milieu. Given the central role of end-stage renal disease (ESRD) …

Intestinal Mϕ play an important role in maintaining gut homeostasis. However, little is known
about these cells, their precursors, and their role in intestinal inflammation. Here, we …

Angiogenesis is a critical step in the development and progression of hepatocellular
carcinoma (HCC). Myeloid lineage cells, such as macrophages and monocytes, have been …

Monocytes represent a heterogeneous population of primary immune effector cells. At least
three different subsets can be distinguished based on expression of the low-affinity FcγRIII …