The idiopathic inflammatory myopathies, including adult and juvenile dermatomyositis (DM),
polymyositis (PM), and inclusion body myositis (IBM), are rare systemic autoimmune …

Polymyositis and dermatomyositis are inflammatory myopathies that differ in their clinical
features, histopathology, response to treatment, and prognosis. Although their clinical …

Background A substantial impediment to progress in trials of new therapies in
neuromuscular disorders is the absence of responsive outcome measures that correlate with …

Conventional MR images are qualitative, and their signal intensity is dependent on several
complementary contrast mechanisms that are manipulated by the MR hardware and …

Recent years have seen tremendous progress towards therapy of many previously incurable
neuromuscular diseases. This new context has acted as a driving force for the development …

Juvenile dermatomyositis, the most common inflammatory myopathy of childhood, is a rare
systemic autoimmune vasculopathy that is characterised by weakness in proximal muscles …

Idiopathic inflammatory myopathies (IIM) are a group of chronic, autoimmune conditions
affecting primarily the proximal muscles. The most common types are dermatomyositis (DM) …

Objectives. To identify epidemiological, clinical and laboratory characteristics of juvenile
dermatomyositis (JDM) in a national multi-centre cohort of patients, and to review recent …

Recently, there have been important advances in the understanding of the pathophysiologic
features, assessment, and management of patients with a newly diagnosed idiopathic …

A major obstacle of allogeneic haematopoietic stem cell transplantation is graft-versus-host
disease, an immune-mediated disorder that affects multiple tissues and organs with varying …