Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Preeclampsia (PE) affects 5–7% of all pregnancies in the United States and is the leading
cause of maternal and prenatal morbidity. PE is associated with hypertension after week 20 …

Introduction The pro‐and anti‐inflammatory cytokines play crucial role in the development
and functions of placenta. Any changes in these cytokines may be associated with many …

IL6 is a multifunctional cytokine with pivotal roles in the inflammatory response and in
directing T cell differentiation in adaptive immunity. IL6 is widely expressed in the female …

Preeclampsia (PE) is an important, common, and dangerous complication of pregnancy; it
causes maternal and perinatal illness and is responsible for a high proportion of maternal …

Problem Published reports testing the association between cytokine levels and
preeclampsia are conflicting. This comprehensive systematic review and meta‐analysis …

MicroRNAs are a class of noncoding small RNAs that regulate the expression of nearly 30%
of all the human genes and participate in all fundamental cell processes. Genome-wide …

Hypoxia is a common and severe stress to an organism's homeostatic mechanisms, and
hypoxia during gestation is associated with significantly increased incidence of maternal …

To demonstrate that pregnancy-related complications are associated with alterations in
placental microRNA expression. Gene expression of 15 C19MC microRNAs (miR-512-5p …

Preeclampsia (PE) is an enigmatic syndrome, still with unknown aetiology and multi-factorial
pathogenesis. Our understanding of the role of the immune system in PE development has …