Spinal cord injury (SCI) often leads to serious motor and sensory dysfunction of the limbs
below the injured segment. SCI not only results in physical and psychological harm to …

The blood–spinal cord barrier (BSCB), a physical barrier between the blood and spinal cord
parenchyma, prevents the toxins, blood cells, and pathogens from entering the spinal cord …

Transected axons are unable to regenerate after spinal cord injury (SCI). Glial scar is
thought to be responsible for this failure. Regulating the formation of glial scar post-SCI may …

Background Microglial polarization with M1/M2 phenotype shifts and the subsequent
neuroinflammatory responses are vital contributing factors for spinal cord injury (SCI) …

Acute spinal cord injury (SCI) is a serious traumatic event to the spinal cord with
considerable morbidity and mortality. This injury leads to short-and long-term variations in …

Exosomes, a kind of extracellular vesicle, are promising therapeutic agents for spinal cord
injury (SCI). This article aimed to investigate effects of exosomes secreted from miRNA-29b …

Spinal cord injury (SCI) is a severe central nervous system injury for which few efficacious
drugs are available. Rosmarinic acid (RA), a water-soluble polyphenolic phytochemical, has …

As the first inflammatory cell recruited to the site of spinal cord injury (SCI), neutrophils were
reported to be detrimental to SCI. However, the precise mechanisms as to how neutrophils …

Spinal cord injury (SCI) is a devastating medical condition with profound social and
economic impacts. Although research is ongoing, current treatment options are limited and …

Baicalin is a natural active ingredient isolated from Scutellariae Radix that can cross the
blood-brain barrier and exhibits neuroprotective effects on multiple central nervous system …