The biosynthetic logic of polyketide diversity

C Hertweck - Angewandte Chemie International Edition, 2009 - Wiley Online Library
Abstract Molecular Lego: Polyketides represent a highly diverse group of natural products
with structurally intriguing carbon skeletons (see picture) which are assembled from simple …

Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases

I Abe, H Morita - Natural product reports, 2010 - pubs.rsc.org
Covering: 2002 to 2009 This review covers recent advances in structure and function studies
on the chalcone synthase (CHS) superfamily of plant type III polyketide synthases (PKSs) …

Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides

SJ Gagne, JM Stout, E Liu, Z Boubakir… - Proceedings of the …, 2012 - National Acad Sciences
Δ9-Tetrahydrocannabinol (THC) and other cannabinoids are responsible for the
psychoactive and medicinal properties of Cannabis sativa L.(marijuana). The first …

[HTML][HTML] Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest

M Xiao, Y Zhang, X Chen, EJ Lee, CJS Barber… - Journal of …, 2013 - Elsevier
Plants produce a vast array of specialized metabolites, many of which are used as
pharmaceuticals, flavors, fragrances, and other high-value fine chemicals. However, most of …

Type III polyketide synthases: functional classification and phylogenomics

Y Shimizu, H Ogata, S Goto - ChemBioChem, 2017 - Wiley Online Library
Polyketide synthases (PKSs) catalyze the sequential condensation of simple acetate units to
produce a large class of natural products, including pharmacologically valuable compounds …

CRISPR/Cas9‐based genome editing of 14 lipid metabolic genes reveals a sporopollenin metabolon ZmPKSB‐ZmTKPR1‐1/‐2 required for pollen exine formation in …

X An, S Zhang, Y Jiang, X Liu, C Fang… - Plant biotechnology …, 2024 - Wiley Online Library
Lipid biosynthesis and transport are essential for plant male reproduction. Compared with
Arabidopsis and rice, relatively fewer maize lipid metabolic genic male‐sterility (GMS) genes …

LAP5 and LAP6 Encode Anther-Specific Proteins with Similarity to Chalcone Synthase Essential for Pollen Exine Development in Arabidopsis

AA Dobritsa, Z Lei, S Nishikawa… - Plant …, 2010 - academic.oup.com
Pollen grains of land plants have evolved remarkably strong outer walls referred to as exine
that protect pollen and interact with female stigma cells. Exine is composed of sporopollenin …

[HTML][HTML] Genome-enabled discovery of anthraquinone biosynthesis in Senna tora

SH Kang, RP Pandey, CM Lee, JS Sim… - Nature …, 2020 - nature.com
Senna tora is a widely used medicinal plant. Its health benefits have been attributed to the
large quantity of anthraquinones, but how they are made in plants remains a mystery. To …

Recent advances in the identification of biosynthetic genes and gene clusters of the polyketide-derived pathways for anthraquinone biosynthesis and biotechnological …

NK Mund, E Čellárová - Biotechnology Advances, 2023 - Elsevier
Natural anthraquinones are represented by a large group of compounds. Some of them are
widespread across the kingdoms, especially in bacteria, fungi and plants, while the others …

[HTML][HTML] The Biochemical and Genetic Basis for the Biosynthesis of Bioactive Compounds in Hypericum perforatum L., One of the Largest Medicinal Crops in Europe

P Rizzo, L Altschmied, BM Ravindran, T Rutten… - Genes, 2020 - mdpi.com
Hypericum perforatum L. commonly known as Saint John's Wort (SJW), is an important
medicinal plant that has been used for more than 2000 years. Although H. perforatum …