Bioelectronic interfaces of organic electrochemical transistors

A Saleh, A Koklu, I Uguz, AM Pappa… - Nature Reviews …, 2024 - nature.com
Organic electrochemical transistors (OECTs) are electronic devices relying on electronic
materials that are stable in aqueous environments. OECTs leverage ionic solutions for their …

Perspectives on systematic optimization of ultrasensitive biosensors through experimental design

M Caputo, A Tricase, V Marchianò… - Journal of Materials …, 2024 - pubs.rsc.org
Biosensors have demonstrated versatility across numerous applications; however, their
systematic optimization remains a primary obstacle, limiting their widespread adoption as …

[HTML][HTML] A versatile approach to quality control of protein-based receptor layers by reversible, nonspecific staining for multiplex SPRi immunosensing

S Karoń, K Porycka, LDS Lapitan Jr, M Drozd… - Sensors and Actuators B …, 2024 - Elsevier
SPRi protein arrays for rapid, label-free immunodetection offer an attractive approach for
high throughput biosensing and analysis of molecular interactions. However, their routine …

Harnessing Bioluminescent Bacteria to Develop an Enzymatic-free Enzyme-linked immunosorbent assay for the Detection of Clinically Relevant Biomarkers

L Hu, M Rossetti, JF Bergua, C Parolo… - … applied materials & …, 2024 - ACS Publications
Enzyme-linked immunosorbent assay (ELISA) is the gold standard technique for measuring
protein biomarkers due to its high sensitivity, specificity, and throughput. Despite its success …

Electric Field Cycling of Physisorbed Antibodies Reduces Biolayer Polarization Dispersion

C Di Franco, E Macchia, M Catacchio… - Advanced …, 2024 - Wiley Online Library
The electric dipoles of proteins in a biolayer determine their dielectric properties through the
polarization density P. Hence, its reproducibility is crucial for applications, particularly in …

Analysis of Clinical Samples of Pancreatic Cyst's Lesions with A Multi‐Analyte Bioelectronic Simot Array Benchmarked Against Ultrasensitive Chemiluminescent …

C Scandurra, K Björkström, M Caputo… - Advanced …, 2024 - Wiley Online Library
Pancreatic cancer, ranking as the third factor in cancer‐related deaths, necessitates
enhanced diagnostic measures through early detection. In response, SiMoT‐Single …

Kelvin probe force microscopy on patterned large-area biofunctionalized surfaces: a reliable ultrasensitive platform for biomarker detection

C Di Franco, M Piscitelli, E Macchia… - Journal of Materials …, 2024 - pubs.rsc.org
Kelvin probe force microscopy (KPFM) allows the detection of single binding events
between immunoglobulins (IgM, IgG) and their cognate antibodies (anti-IgM, anti-IgG). Here …

pH-conditioning of recognition layers enables single-molecule affinity detections at 10E-20 molar

E Macchia, C Di Franco, C Scandurra, L Sarcina… - arXiv preprint arXiv …, 2024 - arxiv.org
While nucleic-acids can be readily amplified for single-marker detection, a comparable
method for proteins assay is currently unavailable. Proteins potentiometric detections at 10 …

β‐Sheets Orientation in Physisorbed Protein Layers

M Piscitelli, D Bajrami, CD Franco, L Sarcina… - Advanced Materials … - Wiley Online Library
Physisorption of antibodies onto surfaces is a low‐cost, rapid, and effective approach for
immobilizing bioreceptors in applications such as bioelectronic sensors. However, there is a …

Electrical Detection of Biomarkers Using Electrolyte-Gated Organic Field-Effect Transistors

K Björkström - 2024 - doria.fi
The work presented in this thesis is based on my research at Physics, Faculty of Science
and Engineering, Åbo Akademi University under the supervision of Ronald Österbacka. For …