Multifunctional and stimuli-sensitive pharmaceutical nanocarriers

V Torchilin - European journal of pharmaceutics and …, 2009 - Elsevier
Currently used pharmaceutical nanocarriers, such as liposomes, micelles, and polymeric
nanoparticles, demonstrate a broad variety of useful properties, such as longevity in the …

Phase‐shift, stimuli‐responsive perfluorocarbon nanodroplets for drug delivery to cancer

N Rapoport - Wiley Interdisciplinary Reviews: Nanomedicine …, 2012 - Wiley Online Library
This review focuses on phase‐shift perfluorocarbon nanoemulsions whose action depends
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …

Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions

N Rapoport, KH Nam, R Gupta, Z Gao, P Mohan… - Journal of Controlled …, 2011 - Elsevier
Perfluorocarbon nanoemulsions can deliver lipophilic therapeutic agents to solid tumors and
simultaneously provide for monitoring nanocarrier biodistribution via ultrasonography and/or …

Polymeric micelles: authoritative aspects for drug delivery

SS Kulthe, YM Choudhari, NN Inamdar… - Designed Monomers …, 2012 - Taylor & Francis
The generation of supramolecular architectures with well-defined structures and
functionalities is recently garnering attraction. Self-assemblage of amphiphilic polymers …

Liposomes in ultrasonic drug and gene delivery

SL Huang - Advanced drug delivery reviews, 2008 - Elsevier
Liposome-based drug and gene delivery systems have potential for significant roles in a
variety of therapeutic applications. Recently, liposomes have been used to entrap gas and …

Cavitation and contrast: the use of bubbles in ultrasound imaging and therapy

EP Stride, CC Coussios - … , Part H: Journal of Engineering in …, 2010 - journals.sagepub.com
Microbubbles and cavitation are playing an increasingly significant role in both diagnostic
and therapeutic applications of ultrasound. Microbubble ultrasound contrast agents have …

Passive imaging with pulsed ultrasound insonations

KJ Haworth, TD Mast, K Radhakrishnan… - The Journal of the …, 2012 - pubs.aip.org
Previously, passive cavitation imaging has been described in the context of continuous-
wave high-intensity focused ultrasound thermal ablation. However, the technique has …

Ultrasound-enhanced thrombolysis with tPA-loaded echogenic liposomes

GJ Shaw, JM Meunier, SL Huang, CJ Lindsell… - Thrombosis research, 2009 - Elsevier
BACKGROUND AND PURPOSE: Currently, the only FDA-approved therapy for acute
ischemic stroke is the administration of recombinant tissue plasminogen activator (tPA) …

Nitric oxide-loaded echogenic liposomes for nitric oxide delivery and inhibition of intimal hyperplasia

SL Huang, PH Kee, H Kim, MR Moody… - Journal of the American …, 2009 - jacc.org
Objectives: We sought to develop a new bioactive gas-delivery method by the use of
echogenic liposomes (ELIP) as the gas carrier. Background: Nitric oxide (NO) is a bioactive …

Physical principles of microbubbles for ultrasound imaging and therapy

E Stride - Cerebrovascular Diseases, 2009 - karger.com
Microbubble ultrasound contrast agents have been in clinical use for more than two
decades, during which time their range of applications has increased to encompass …