Genome editing by sequence-specific nucleases (SSNs) has revolutionized biology by
enabling targeted modifications of genomes. Although routine plant genome editing …

Loss-of-function mutations of one or more of the appropriate Mildew resistance locus o (Mlo)
genes are an apparently reliable “weapon” to protect plants from infection by powdery …

Disruption of susceptibility (S) genes in crops is an attractive breeding strategy for conferring
disease resistance,. However, S genes are implicated in many essential biological functions …

The plant response to attempted infection by microbial pathogens is often accompanied by
rapid cell death in and around the initial infection site, a reaction known as the …

G-protein-coupled receptors (GPCRs) represent one of the largest gene families in the
animal genome. These receptors can be classified into several groups based on the …

The identification of two Arabidopsis thaliana genes involved in determining recessive
resistance to several strains of the causal agent of bacterial wilt, Ralstonia solanacearum, is …

Stable heritable restriction of the ubiquitous powdery mildew disease is a desirable trait for
agri‐and horticulture. In barley (H ordeum vulgare), loss‐of‐function mutant alleles of the …

Few plant pathogens have had a more profound effect on the evolution of disease
management than Erysiphe necator, which causes grapevine powdery mildew. When the …

In animals, heterotrimeric G proteins, comprising α-, β-and γ-subunits, perceive extracellular
stimuli through cell surface receptors, and transmit signals to ion channels, enzymes and …

Erysiphe necator is the causal agent of powdery mildew (PM), one of the most destructive
diseases of grapevine. PM is controlled by sulfur-based and synthetic fungicides, which …