Vagal sensory neurons and gut-brain signaling

DY Chuyue, QJ Xu, RB Chang - Current opinion in neurobiology, 2020 - Elsevier
Highlights• The vagus nerve is a crucial link between gut signals and the brain regulating
various functions such as energy homeostasis, digestion, immune responses, reward …

Enteric nervous system-derived IL-18 orchestrates mucosal barrier immunity

A Jarret, R Jackson, C Duizer, ME Healy, J Zhao… - Cell, 2020 - cell.com
Mucosal barrier immunity is essential for the maintenance of the commensal microflora and
combating invasive bacterial infection. Although immune and epithelial cells are thought to …

The diversity of neuroimmune circuits controlling lung inflammation

M Cremin, S Schreiber, K Murray… - … of Physiology-Lung …, 2023 - journals.physiology.org
It is becoming increasingly appreciated that the nervous and immune systems communicate
bidirectionally to regulate immunological outcomes in a variety of organs including the lung …

Biomimetic Gut Model Systems for Development of Targeted Microbial Solutions for Enhancing Warfighter Health and Performance

LM Brinkac, N Rahman, LL Chua, S Thomas - Msystems, 2020 - Am Soc Microbiol
The human gut microbiome plays a vital role in both health and disease states and as a
mediator of cognitive and physical performance. Despite major advances in our …

Regulatory T cells shape the CD4 T cell response to Salmonella

SL Clay - 2019 - theses.gla.ac.uk
FoxP3+ regulatory T cells (Tregs) play an important role in controlling inflammation and
maintaining homeostasis at mucosal sites. Tregs may also limit immunopathology during …