[HTML][HTML] The emerging role of the long non-coding RNA HOTAIR in breast cancer development and treatment
H Mozdarani, V Ezzatizadeh… - Journal of translational …, 2020 - Springer
Despite considering vast majority of the transcribed molecules as merely noise RNA in the
last decades, recent advances in the field of molecular biology revealed the mysterious role …
last decades, recent advances in the field of molecular biology revealed the mysterious role …
[HTML][HTML] Non-coding RNAs in immunoregulation and autoimmunity: Technological advances and critical limitations
Immune cell function is critically dependent on precise control over transcriptional output
from the genome. In this respect, integration of environmental signals that regulate gene …
from the genome. In this respect, integration of environmental signals that regulate gene …
[HTML][HTML] Identification of LncRNA Linc00513 containing lupus-associated genetic variants as a novel regulator of interferon signaling pathway
Z Xue, C Cui, Z Liao, S Xia, P Zhang, J Qin… - Frontiers in …, 2018 - frontiersin.org
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by
augmented type I interferon signaling. High-throughput technologies have identified plenty …
augmented type I interferon signaling. High-throughput technologies have identified plenty …
HOTAIR beyond repression: In protein degradation, inflammation, DNA damage response, and cell signaling
RL Price, A Bhan, SS Mandal - DNA repair, 2021 - Elsevier
Long noncoding RNAs (lncRNAs) are pervasively transcribed from the mammalian genome
as transcripts that are usually> 200 nucleotides long. LncRNAs generally do not encode …
as transcripts that are usually> 200 nucleotides long. LncRNAs generally do not encode …
[HTML][HTML] Long non-coding RNA HOTAIR in central nervous system disorders: new insights in pathogenesis, diagnosis, and therapeutic potential
J Wang, J Zhao, P Hu, L Gao, S Tian… - Frontiers in Molecular …, 2022 - frontiersin.org
Central nervous system (CNS) disorders, such as ischemic stroke, neurodegenerative
diseases, multiple sclerosis, traumatic brain injury, and corresponding neuropathological …
diseases, multiple sclerosis, traumatic brain injury, and corresponding neuropathological …
[HTML][HTML] Vitamin D may protect against breast cancer through the regulation of long noncoding RNAs by VDR signaling
J Blasiak, J Chojnacki, E Pawlowska… - International Journal of …, 2022 - mdpi.com
Dietary vitamin D3 has attracted wide interest as a natural compound for breast cancer
prevention and therapy, supported by in vitro and animal studies. The exact mechanism of …
prevention and therapy, supported by in vitro and animal studies. The exact mechanism of …
Critical role of HOX transcript antisense intergenic RNA (HOTAIR) in gliomas
E Angelopoulou, YN Paudel, C Piperi - Journal of Molecular Medicine, 2020 - Springer
Despite extensive research, gliomas are associated with high morbidity and mortality, mainly
attributed to the rapid growth rate, excessive invasiveness, and molecular heterogeneity, as …
attributed to the rapid growth rate, excessive invasiveness, and molecular heterogeneity, as …
LncRNA HOX transcript antisense RNA accelerated kidney injury induced by urine-derived sepsis through the miR-22/high mobility group box 1 pathway
J Shen, J Zhang, X Jiang, H Wang, G Pan - Life sciences, 2018 - Elsevier
Objective This study investigated the role of long noncoding RNA (lncRNA) HOX transcript
antisense RNA (HOTAIR) in kidney injury induced by urine-derived sepsis (US). Materials …
antisense RNA (HOTAIR) in kidney injury induced by urine-derived sepsis (US). Materials …
LncRNAs expression profile in peripheral blood mononuclear cells from multiple sclerosis patients
C Fenoglio, E Oldoni, M Serpente, A Milena… - Journal of …, 2018 - Elsevier
LncRNA PCR arrays containing 90 common LncRNAs were used to screen lncRNA
expression levels in PBMC from a discovery population of patients with MS. Data from …
expression levels in PBMC from a discovery population of patients with MS. Data from …
[HTML][HTML] The microRNA centrism in the orchestration of neuroinflammation in neurodegenerative diseases
N Nuzziello, M Liguori - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs with a unique ability to regulate the
transcriptomic profile by binding to complementary regulatory RNA sequences. The ability of …
transcriptomic profile by binding to complementary regulatory RNA sequences. The ability of …