[HTML][HTML] Tomatoes: An extensive review of the associated health impacts of tomatoes and factors that can affect their cultivation

EJ Collins, C Bowyer, A Tsouza, M Chopra - Biology, 2022 - mdpi.com
Simple Summary The research outlined in this review paper discusses potential health
benefits associated with a diet enriched with tomatoes and tomato products. This includes …

Pharmacological potentials of lycopene against aging and aging‐related disorders: A review

MH Abir, AGMSU Mahamud, SH Tonny… - Food Science & …, 2023 - Wiley Online Library
Aging and aging‐related chronic disorders are one of the principal causes of death
worldwide. The prevalence of these disorders is increasing gradually and globally …

Synergistic effects of carotenoids: Therapeutic benefits on human health

F Islam, J Khan, M Zehravi, R Das, MA Haque… - Process …, 2023 - Elsevier
Carotenoids are naturally occurring compounds that are abundant and possess synergistic
properties, contributing to their potential health benefits. This review provides an analysis of …

Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF‐кB Signaling Pathway in High‐Fat Diet‐Induced Obese Mice

B Xia, R Zhu, H Zhang, B Chen, Y Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
Objective. This study was aimed at examining the effects of lycopene on bone metabolism in
high‐fat diet (HFD)‐induced obese mice and to identify the potential underlying …

Lycopene ameliorates islet function and down-regulates the TLR4/MyD88/NF-κB pathway in diabetic mice and Min6 cells

Y Liu, Y Tian, X Dai, T Liu, Y Zhang, S Wang, H Shi… - Food & Function, 2023 - pubs.rsc.org
The inflammation of the pancreatic islets triggers β cell dysfunction and type 2 diabetes
mellitus (T2DM) onset. While dietary lycopene consumption contributes to protection against …

[HTML][HTML] Effect of carotenoids on paraoxonase-1 activity and gene expression

A Otocka-Kmiecik - Nutrients, 2022 - mdpi.com
Paraoxonase 1 (PON1) is an antioxidant enzyme attached to HDL with an anti-atherogenic
potential. It protects LDL and HDL from lipid peroxidation. The enzyme is sensitive to various …

Lycopene ameliorates skin aging by regulating the insulin resistance pathway and activating SIRT1

J Li, X Zeng, X Yang, H Ding - Food & Function, 2022 - pubs.rsc.org
Microvascular loss is one of the most important characteristics of skin aging and several
microvascular activities play key roles in preserving skin health. In vitro, lycopene (Ly) …

[HTML][HTML] Combined effects of lycopene and metformin on decreasing oxidative stress by triggering endogenous antioxidant defenses in diet-induced obese mice

BP Motta, CG Pinheiro, ID Figueiredo, FN Cardoso… - Molecules, 2022 - mdpi.com
Since lycopene has antioxidant activity, its combination with metformin may be useful to
contrast diabetic complications related to oxidative stress. This study aimed to investigate …

[HTML][HTML] Hydroxyethylcellulose-based hydrogels containing liposomes functionalized with cell-penetrating peptides for nasal delivery of insulin in the treatment of …

ES Von Zuben, JO Eloy, MD Inácio, VHS Araujo… - Pharmaceutics, 2022 - mdpi.com
Liposomes functionalized with cell-penetrating peptides are a promising strategy to deliver
insulin through the nasal route. A hydrogel based on hydroxyethylcellulose (HEC) aqueous …

Lycopene: Extraction, microencapsulation, and therapeutic properties

B Khongthaw, PK Chauhan, K Dulta, V Kumar… - Bioresource Technology …, 2024 - Elsevier
Lycopene, an antioxidant carotenoid, possesses a unique acyclic structure that imparts
lipophilic characteristics, making it soluble in organic solvents. However, challenges arise in …