Dual COX-2/15-LOX inhibitors: A new avenue in the prevention of cancer
A Aliabadi, E Khanniri, M Mahboubi-Rabbani… - European journal of …, 2023 - Elsevier
Abstract Dual cyclooxygenase 2/15-lipoxygenase inhibitors constitute a valuable alternative
to classical non-steroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 …
to classical non-steroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 …
Critical review on anti‐inflammation effects of saponins and their molecular mechanisms
This review highlights the increasing interest in one of the natural compounds called
saponins, for their potential therapeutic applications in addressing inflammation which is a …
saponins, for their potential therapeutic applications in addressing inflammation which is a …
Computational screening of potential anti-inflammatory leads from Jeevaneeya Rasayana plants targeting COX-2 and 5-LOX by molecular docking and dynamic …
Inflammation plays a pivotal role in various pathological processes, ranging from routine
injuries and infections to cancer. Cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) …
injuries and infections to cancer. Cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) …
Explainable artificial intelligence-assisted virtual screening and bioinformatics approaches for effective bioactivity prediction of phenolic cyclooxygenase-2 (COX-2) …
Abstract Cyclooxygenase-2 (COX-2) inhibitors are nonsteroidal anti-inflammatory drugs that
treat inflammation, pain and fever. This study determined the interaction mechanisms of …
treat inflammation, pain and fever. This study determined the interaction mechanisms of …
Receptor-based pharmacophore modeling, molecular docking, synthesis and biological evaluation of novel VEGFR-2, FGFR-1, and BRAF multi-kinase inhibitors
HT Abdel-Mohsen, MA Ibrahim, AM Nageeb… - BMC chemistry, 2024 - Springer
A receptor-based pharmacophore model describing the binding features required for the
multi-kinase inhibition of the target kinases (VEGFR-2, FGFR-1, and BRAF) were …
multi-kinase inhibition of the target kinases (VEGFR-2, FGFR-1, and BRAF) were …
Anti-Parkinson potential of hesperetin nanoparticles: in vivo and in silico investigations
PK Pasala, DSNBK Prasanth, M Rudrapal… - Natural Product …, 2024 - Taylor & Francis
Parkinson's disease (PD) is characterised by the gradual demise of dopaminergic neurons.
In recent years, there has been significant interest in herbal treatments. In this study …
In recent years, there has been significant interest in herbal treatments. In this study …
In vitro Genotoxicity and In silico Docking Analyses of the Essential Oils of Thuja orientalis
S Bozari - Chemistry & Biodiversity, 2024 - Wiley Online Library
Two main objectives were pursued to assess the reliability of Thuja orientalis essential oils
(TOEO). The first objective was to extract TOEO, analyze them by GC‐MS, and determine …
(TOEO). The first objective was to extract TOEO, analyze them by GC‐MS, and determine …
[HTML][HTML] In silico identification of potential PvFKBP35 inhibitors from Entadrophragma angolense Limonoids extracts as antimalarial agents
Plasmodium species, which are spread by female Anopheles mosquitoes, are responsible
for malaria. Out of the five major Plasmodium species, Plasmodium falciparum and …
for malaria. Out of the five major Plasmodium species, Plasmodium falciparum and …
Bio synthesis, comprehensive characterization, and multifaceted therapeutic applications of BSA-Resveratrol coated platinum nanoparticles
This study examines the manufacturing, characterization, and biological evaluation of
platinum nanoparticles, which were synthesized by Enterobacter cloacae and coated with …
platinum nanoparticles, which were synthesized by Enterobacter cloacae and coated with …
[HTML][HTML] In-silico and in-vivo comparative evaluation of the cardioprotective potential of Yellow turmeric and White turmeric in Mn-induced cardiac oxidative stress
TT Fasooto, OR Ogundana, AF Adebayo… - Pharmacological …, 2024 - Elsevier
Introduction The effect of the ethanol extracts of Curcuma longa Linn (yellow turmeric) and
Curcuma zedoaria Rosc (white turmeric) on cardiac oxidative stress in rats exposed to …
Curcuma zedoaria Rosc (white turmeric) on cardiac oxidative stress in rats exposed to …