Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …

Significant experimental, computational, and theoretical work has identified rich structure
within the coordinated activity of interconnected neural populations. An emerging challenge …

Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …

Decades of neurobiological research have disclosed the diverse manners in which the
response properties of neurons are dynamically modulated to support adaptive cognitive …

A central goal of neuroscience is to understand the representations formed by brain activity
patterns and their connection to behaviour. The classic approach is to investigate how …

For over a century, the neuron doctrine—which states that the neuron is the structural and
functional unit of the nervous system—has provided a conceptual foundation for …

Most sensory, cognitive and motor functions depend on the interactions of many neurons. In
recent years, there has been rapid development and increasing use of technologies for …

Prefrontal cortex is thought to have a fundamental role in flexible, context-dependent
behaviour, but the exact nature of the computations underlying this role remains largely …

While isolated motor actions can be correlated with activities of neuronal networks, an
unresolved problem is how the brain assembles these activities into organized behaviors …

Most theories of motor cortex have assumed that neural activity represents movement
parameters. This view derives from what is known about primary visual cortex, where neural …