A narrative review on trans-nasal pulmonary aerosol delivery

J Li, JB Fink, R MacLoughlin, R Dhand - Critical Care, 2020 - Springer
The use of trans-nasal pulmonary aerosol delivery via high-flow nasal cannula (HFNC) has
expanded in recent years. However, various factors influencing aerosol delivery in this …

First-time handling of different inhalers by chronic obstructive lung disease patients

HS Harb, NI Laz, H Rabea… - Experimental Lung …, 2020 - Taylor & Francis
Background: There is a lack of guidance on inhaler device selection and how to
individualize inhaler choice when prescribed for the first-time. Aim of the work: To compare …

Update efficacy of aerosol therapy with noninvasive ventilator approach (non-invasive ventilation and nasal high flow)

HS Harb, H Saeed, YM Madney… - Journal of Drug Delivery …, 2020 - Elsevier
Aerosol delivery by nebulizers and pressurized metered-dose inhalers (pMDIs) attached
through an adapter or spacer into a ventilation circuit during noninvasive mechanical …

Prevalence and predictors of suboptimal peak inspiratory flow rate in COPD patients

HS Harb, NI Laz, H Rabea, MEA Abdelrahim - European Journal of …, 2020 - Elsevier
The aim of this study was to determine prevalence and possible clinical predictors of
suboptimal peak inspiratory flow rate (PIFR) with different dry powder inhalers. PIFR was …

The influence of changing interfaces on aerosol delivery within high flow oxygen setting in adults: an in-vitro study

YM Madney, NI Laz, AA Elberry, H Rabea… - Journal of Drug Delivery …, 2020 - Elsevier
Despite the fact that the nasal-cannula is more comfortable than facemask, using facemask
with high flow oxygen therapy (HFOT) may be beneficial in mouth-breathers. The aim of the …

Aerosol delivery through an adult high-flow nasal cannula circuit using low-flow oxygen

YM Madney, M Fathy, AA Elberry, H Rabea… - Respiratory …, 2019 - rc.rcjournal.com
BACKGROUND: There has been a growing trend toward delivering aerosolized medications
using high-flow nasal cannula (HFNC). In some cases, patients who do not require high-flow …

Effects of fill volume and humidification on aerosol delivery during single-limb noninvasive ventilation

H Saeed, M Mohsen, AS Eldin, AA Elberry… - Respiratory …, 2018 - rc.rcjournal.com
BACKGROUND: The aim of this work was to determine the effect of fill volume and
humidification change on aerosol delivery during single-limb noninvasive ventilation (NIV) …

Modeling and optimization of nebulizers' performance in non-invasive ventilation using different fill volumes: comparative study between vibrating mesh and jet …

H Saeed, AMA Ali, AA Elberry, AS Eldin… - Pulmonary …, 2018 - Elsevier
Backgrounds Substituting nebulisers by another, especially in non-invasive ventilation (NIV),
involves many process-variables, eg nebulizer-type and fill-volume of respirable-dose …

Inhaled salbutamol dose delivered by jet nebulizer, vibrating mesh nebulizer and metered dose inhaler with spacer during invasive mechanical ventilation

MHE ElHansy, ME Boules, AFM El Essawy… - Pulmonary …, 2017 - Elsevier
Background Patient receiving invasive mechanical ventilation (IMV) may benefit from
medical aerosol, but guidance on dosing with different aerosol devices is limited to in-vitro …

Lung deposition and systemic bioavailability of different aerosol devices with and without humidification in mechanically ventilated patients

IOF Moustafa, MRAA Ali, M Al Hallag, H Rabea, JB Fink… - Heart & Lung, 2017 - Elsevier
Background During mechanical ventilation medical aerosol delivery has been reported to be
upto two fold greater with dry inhaled gas than with heated humidity. Urine levels at 0.5 h …