Multiple sequence alignment modeling: methods and applications

M Chatzou, C Magis, JM Chang… - Briefings in …, 2016 - academic.oup.com
This review provides an overview on the development of Multiple sequence alignment
(MSA) methods and their main applications. It is focused on progress made over the past …

The extent of mycorrhizal colonization of roots and its influence on plant growth and phosphorus content

KK Treseder - Plant and Soil, 2013 - Springer
Aims The most common metric of arbuscular mycorrhizal fungal (AMF) abundance is percent
root length colonized (PRLC) by mycorrhizal structures. Frequently, plants with greater …

The EFI web resource for genomic enzymology tools: leveraging protein, genome, and metagenome databases to discover novel enzymes and metabolic pathways

R Zallot, N Oberg, JA Gerlt - Biochemistry, 2019 - ACS Publications
The assignment of functions to uncharacterized proteins discovered in genome projects
requires easily accessible tools and computational resources for large-scale, user-friendly …

American gut: an open platform for citizen science microbiome research

D McDonald, E Hyde, JW Debelius, JT Morton… - Msystems, 2018 - Am Soc Microbiol
Although much work has linked the human microbiome to specific phenotypes and lifestyle
variables, data from different projects have been challenging to integrate and the extent of …

Whole-genome analyses resolve early branches in the tree of life of modern birds

ED Jarvis, S Mirarab, AJ Aberer, B Li, P Houde, C Li… - Science, 2014 - science.org
To better determine the history of modern birds, we performed a genome-scale phylogenetic
analysis of 48 species representing all orders of Neoaves using phylogenomic methods …

GUIDANCE2: accurate detection of unreliable alignment regions accounting for the uncertainty of multiple parameters

I Sela, H Ashkenazy, K Katoh, T Pupko - Nucleic acids research, 2015 - academic.oup.com
Inference of multiple sequence alignments (MSAs) is a critical part of phylogenetic and
comparative genomics studies. However, from the same set of sequences different MSAs …

Early photosynthetic eukaryotes inhabited low-salinity habitats

P Sánchez-Baracaldo, JA Raven… - Proceedings of the …, 2017 - National Acad Sciences
The early evolutionary history of the chloroplast lineage remains an open question. It is
widely accepted that the endosymbiosis that established the chloroplast lineage in …

Phylogeny-aware alignment with PRANK

A Löytynoja - Multiple sequence alignment methods, 2014 - Springer
Evolutionary analyses require sequence alignments that correctly represent evolutionary
homology. Evolutionary and structural homology are not the same and sequence alignments …

PhyloPhlAn is a new method for improved phylogenetic and taxonomic placement of microbes

N Segata, D Börnigen, XC Morgan… - Nature …, 2013 - nature.com
New microbial genomes are constantly being sequenced, and it is crucial to accurately
determine their taxonomic identities and evolutionary relationships. Here we report …

PASTA: ultra-large multiple sequence alignment

S Mirarab, N Nguyen, T Warnow - … 2014, Pittsburgh, PA, USA, April 2-5 …, 2014 - Springer
In this paper, we introduce a new and highly scalable algorithm, PASTA, for large-scale
multiple sequence alignment estimation. PASTA uses a new technique to produce an …